52046-57-8

Usage

Category

Diketones

Structure

A brominated derivative of 1,3-Propanedione with two 4-methoxyphenyl groups attached to the carbon atoms

Usage

Building block in organic synthesis

Applications

Production of pharmaceuticals, agrochemicals, and other industrial applications

Hazardous Nature

Potentially hazardous chemical

Toxicity

Identified for its toxicity and potential health effects

Precautions

Proper handling and usage measures should be taken to minimize risks

Safety Measures

Use personal protective equipment (PPE) and follow safety guidelines when working with this substance

Upstream product

• 100-07-2 4-methoxy-benzoyl chloride 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 121-98-2 methyl 4-methoxybenzoate 
• 18362-51-1 1,3-bis(4'-methoxyphenyl)propane-1,3-dione 

Downstream Products

• 15850-41-6 4-Methoxy-N-[4-(4-methoxy-phenyl)-thiazol-2-yl]-benzamide 
• 123084-36-6 (2-amino-4-(4-methoxyphenyl)thiazol-5-yl)(4-methoxyphenyl)methanone 
• 54519-16-3 2,2-Diacetoxy-1,3-di-(p-methoxyphenyl)-propan-1,3-dion 
• 52046-60-3 2-Acetoxy-1,3-di--propan-1,3-dion 
• 583878-65-3 1,3,4,6-tetrakis(4'-methoxyphenyl)-2λ⁴δ²-thieno[3,4-c]thiophene 
• 16197-83-4 4,4'-dimethoxy-β-methylchalcone 
• 141221-88-7 1,4-bis(4'-methoxyphenyl)-2,3-bis(4'-methoxybenzoyl)butane-1,4-dione 
• 54519-18-5 4,4'-dimethoxydibenzoylmethane 
• 84474-72-6 Pyridinium-bis(4-methoxybenzoyl)methanid 
• 29574-61-6 1,3-Bis(4-methoxyphenyl)-1,2,3-propantrion 

Relevant academic research and scientific papers

Solvent-Controlled α-Monobromination, α,α-Dibromination or Imidation of 1,3-Diketones with N-Bromosuccinimide

In this work, we present a solvent-controlled regioselective method for α-monobromination, dibromination or imidation of 1,3-diketones with N-bromosuccinimide under simple reaction conditions. The employment of solvents plays a key role on the reaction selectivity providing α-monobrominated, dibrominated and imidated products. Visible light irradiation accelerates the dibromination reaction of 1,3-diketones. In particular, one important solvent was found to be highly effective for the imidation of 1,3-diketones under base-free condition.

Synthesis and study of the anodic behavior of 1,3,4,6-tetraaryl-2λ4δ2-thieno[3,4-c] thiophenes

Two heterocyclic compounds based on the thieno[3,4-c]thiophene structure with four aryl substituents were prepared and their behavior in electrooxidation studied. These tetraarylthieno[3,4-c]thiophenes were synthesized in three steps starting from 1,3-dibenzoylmethane in the case of 1,3,4,6-tetraphenyl-2λ4δ2-thieno[3,4-c] thiophene 1a and from 1,3-bis(4′-methoxyphenyl)propane-1,3-dione in the case of 1,3,4,6-tetrakis(4′-methoxyphenyl)-2λ4δ 2-thieno[3,4-c]thiophene 1b, a new compound. Both cyclic and hydrodynamic voltamperometric analyses indicate two reversible one-electron oxidation stages for compound 1b, while for compound 1a only the first stage is reversible. The preparative electrooxidation of the two compounds results in the opening of one thiophene ring giving rise to γ-keto-thioketones.