52049-50-0Relevant academic research and scientific papers
First example of long distance stereocontrolled synthesis in 1-aza-3,7-dioxabicyclo[3.3.0.]octane series
Maiereanu, Carmen,Darabantu, Mircea,Condamine, Eric,Ple, Gerard,Ramondenc, Yvan,Fazekas, Marijana,Pintea, Monica,Berghian, Camelia
, p. 305 - 310 (2005)
The diastereoselective synthesis of (1R*,1′S*,2S*, 2′R*,5S*,5′R*,8R*,8′S*)-bis-1, 4-{1-aza-5-methyl-8-(4-nitrophenyl)-3,7-dioxabicyclo[3.3.0]octane-2-yl}benzene is described as the first example of a long distance stereocontrolled synthesis of this type of structure. The thermodynamic control of the reaction together with complete NMR evidence to support the stereochemistry of this compound are discussed.
