52098-88-1

Usage

Chemical compound

2-amino-3-(aminomethyl)benzonitrile

Physical state

Colorless to pale yellow liquid

Uses

Intermediate in production of dyes, polymers, and pharmaceuticals

Chemical structure

Contains a benzene ring with an attached amino group

Safety

Irritant to skin, eyes, and respiratory system; proper safety precautions required

Health risks

Identified as a potential human carcinogen; may pose risks with prolonged or repeated exposure

Upstream product

• 16313-65-8 2-amino-5-nitrobenzamide 
• 4403-69-4 2-amino-1-benzylamine 
• 17420-30-3 5-nitroanthranilonitrile 
• 52098-87-0 2-Acetamidomethyl-4-nitroacetanilid 

Downstream Products

• 129490-16-0 8-nitroisoindolo<1,2-b>quinazolin-12(10H)-one 
• 863771-09-9 5-nitro-2-amino-benzylamine hydrochloride 
• 1586823-99-5 C₂₁H₁₅N₃O₃S 
• 1586824-00-1 C₂₂H₁₇N₃O₃S 
• 1586824-01-2 C₂₅H₂₃N₃O₃S 
• 1586824-02-3 C₂₂H₁₇N₃O₄S 
• 1586824-04-5 C₂₁H₁₄FN₃O₃S 
• 1586824-05-6 C₂₁H₁₄N₄O₅S 
• 1225193-84-9 tert-butyl 2-amino-5-nitrobenzylcarbamate 
• 863771-06-6 6-nitro-2-phenylquinazoline 
• 67199-66-0 batracylin 
• 52098-84-7 (2-Amino-5-nitrobenzyl)dithiocarbaminsaeure 

Relevant academic research and scientific papers

HIGH STRESS RESISTANT PLANT GROWTH REGULATOR AND PREPARATION METHOD AND USE THEREOF

Disclosed are a high stress resistant plant growth regulator and a preparation and use thereof. In particular, the compound provided by the present invention is an ABA substitute for significantly improving the stress resistance of plants, and therefore has a very wide application prospect.

Base-Promoted Synthesis of 2-Aryl Quinazolines from 2-Aminobenzylamines in Water

A transition-metal-free procedure for the synthesis of a highly valuable class of heteroaromatics, quinazolines, was developed by using easily available 2-aminobenzylamines and α,α,α-trihalotoluenes. The transformation proceeded smoothly in the presence of only sodium hydroxide and molecular oxygen in water at 100 °C, furnishing a variety of 2-aryl quinazolines. The crystallization process of the crude reaction mixture for the purification of the solid products circumvents huge solvent-consuming workup and column chromatographic techniques, which make the overall process more sustainable and economical.

New Dimamine compd.

Disclosed is a liquid crystal aligning agent which can provide, without addition of a crosslinking agent, a liquid crystal alignment film that has excellent mechanical strength and is not easily scratched by rubbing.? The liquid crystal aligning agent can

Synthesis of batracylin and its N-sulfonamido analogues in [b-3C-im][NTf2] ionic liquid

Starting with commercial and inexpensive reagents, a high-yielding chemical process carried out in [b-3C-im][NTf2] ionic liquid was achieved to afford the synthesis of batracylin and its N-sulfonamido analogues. Among all compounds synthesized, compounds 1, 11, and 14 exhibit potent inhibitory activity against human topoisomerase 1 (hTop1).

Hepatitis C NS5B polymerase inhibitors: Functional equivalents for the benzothiadiazine moiety

A series of quinoline derivatives was synthesized as potential bioisosteric replacements for the benzothiadiazine moiety of earlier Hepatitis C NS5B polymerase inhibitors. Several of these compounds exhibited potent activity in enzymatic and replicon assays.

6-1H-IMIDAZO-QUINAZOLINE AND QUINOLINES DERIVATIVES, NEW POTENT ANALGESICS AND ANTI-INFLAMMATORY AGENTS

The present invention is directed to novel 6-lH-imidazo-2- aryl and 2-heteroaryl quinazoline and quinoline of Formula (I), corresponding salts and solvates thereof, to a process for their preparation and to the use of this compounds and corresponding phar