52121-66-1Relevant academic research and scientific papers
Nickel-catalyzed guerbet type reaction: C-alkylation of secondary alcohols via double (de)hydrogenation
Babu, Reshma,Subaramanian, Murugan,Midya, Siba P.,Balaraman, Ekambaram
supporting information, p. 3320 - 3325 (2021/05/31)
Acceptorless double dehydrogenative cross-coupling of secondary and primary alcohols under nickel catalysis is reported. This Guerbet type reaction provides an atom- and a step-economical method for the C-alkylation of secondary alcohols under mild, benign conditions. A broad range of substrates including aromatic, cyclic, acyclic, and aliphatic alcohols was well tolerated. Interestingly, the C-alkylation of cholesterol derivatives and the double C-alkylation of cyclopentanol with various alcohols were also demonstrated.
3-Methylcyclohex-2-enone Derivatives as Initiators of Cyclisation. Part 4. Some Bicyclisations
Amupitan, Joseph A.,Beddoes, Roy L.,Mills, Owen S.,Sutherland, James K.
, p. 759 - 764 (2007/10/02)
Hydrochrysene and hydrophenanthrene derivatives (8)-(14) have been prepared by cyclisation of 2-substituted 3-methylcyclohexen-2-ones and the derived 2,3-epoxides.Cyclisation of the epoxides does not give preparatively useful yields of bicyclised compound
Aryl substituted diketones
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, (2008/06/13)
Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester.
Dialkylaminophenylethyl (or vinyl) cyclopropyl carbinols
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, (2008/06/13)
Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester. The intermediate iodides are prepared by cond
Methylenedioxyphenyl substituted aliphatic diketones
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, (2008/06/13)
Aryl substituted diketones and keto-esters, useful as antiviral agents and insecticides, are prepared by reacting an arylalkyl or arylalkenyl iodide with a metal salt of the appropriate diketone or keto-ester.
Aryl substituted ketones
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, (2008/06/13)
Aryl substituted tertiary carbinols, useful as antiviral agents and insecticides, are prepared by reacting the Grignard reagent derived from an arylalkyl or arylalkenyl iodide with a dialkyl ketone or an alkyl alkenyl ketone; or by reacting an arylalkyl or arylalkenyl ketone with an alkyl- or alkenylmagnesium halide.
Antivital activity of some β diketones. I. Aryl alkyl diketones. In vitro activity against both RNA and DNA viruses
Diana,Salvador,Zalay,et al.
, p. 750 - 756 (2007/10/05)
The discovery that 4 [3 ethyl 6 [(3,4 methylenedioxy)phenyl] 3 hexenyl] 3,5 heptanedione exhibited an in vitro inhibitory effect against equine rhinovirus led to a structure activity study to establish the criteria for optimum activity. Modification of th
