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2,3,5,6-Tetrafluoro-4-(trifluoromethyl)benzoic acid is a fluorinated aromatic carboxylic acid with the molecular formula C8H2F7O2. It features a benzene ring with four fluorine atoms at the 2, 3, 5, and 6 positions and a trifluoromethyl group attached at the 4 position. This chemical compound is known for its unique chemical and physical properties due to the presence of fluorine atoms, making it a valuable ingredient in various industrial applications.

5216-22-8

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5216-22-8 Usage

Uses

Used in Pharmaceutical Industry:
2,3,5,6-Tetrafluoro-4-(trifluoromethyl)benzoic acid is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties contribute to the development of new drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 2,3,5,6-tetrafluoro-4-(trifluoromethyl)benzoic acid serves as a building block for the production of agrochemicals, such as pesticides and herbicides. Its fluorinated nature enhances the stability and performance of these chemicals in agricultural applications.
Used in Materials Science:
2,3,5,6-Tetrafluoro-4-(trifluoromethyl)benzoic acid is utilized in the development of advanced materials, including polymers and coatings, due to its chemical resistance, thermal stability, and other desirable properties.
Used in Organic Synthesis:
2,3,5,6-TETRAFLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID is employed as a versatile building block in organic synthesis, allowing the creation of a wide range of specialty chemicals and fine chemicals for various applications.
Used in Catalysis:
2,3,5,6-Tetrafluoro-4-(trifluoromethyl)benzoic acid also finds applications in the field of catalysis, where its unique properties can enhance the efficiency and selectivity of chemical reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 5216-22-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,1 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5216-22:
(6*5)+(5*2)+(4*1)+(3*6)+(2*2)+(1*2)=68
68 % 10 = 8
So 5216-22-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H8BrNO3/c1-2-9(12)7-4-3-6(10)5-8(7)11(13)14/h3-5H,2H2,1H3

5216-22-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3,5,6-TETRAFLUORO-4-(TRIFLUOROMETHYL)BENZOIC ACID

1.2 Other means of identification

Product number -
Other names PC0506

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5216-22-8 SDS

5216-22-8Relevant academic research and scientific papers

Preparation of first examples of RFCCIF4 molecules. A study of the fluorination of selected 1-iodoalk-1-ynes with xenon difluoride/boron trifluoride

Bardin, Vadim V.,Frohn, Hermann-Josef

, p. 98 - 104 (2013/04/10)

First examples of alk-1-yn-1-yliodine(V) molecules, CF3CCIF 4 and C6F13CCIF4, were prepared by fluorination of the corresponding 1-iodoperfluoroalk-1-ynes with XeF2 in 1,1,1,3,3-pentafluoro

Transformation of perfluorinated benzocycloalkenes and alkylbenzenes to their carbonyl derivatives under the action of CF3COOH/SbF5

Zonov, Yaroslav V.,Karpov, Victor M.,Platonov, Vyacheslav E.

, p. 1058 - 1064 (2008/02/10)

Perfluorinated benzocycloalkenes (benzocyclobutene, indan, tetralin), alkylbenzocycloalkenes and alkylbenzenes react with CF3COOH/SbF5 at 20-50 °C giving the corresponding carbonyl derivatives.

REACTION OF PERFLUORINATED METHYL- AND ALKENYLBENZENES WITH INORGANIC OXIDES IN THE PRESENCE OF ANTIMONY PENTAFLUORIDE

Karpov, V. M.,Panteleev, I. V.,Platonov, V. E.

, p. 1932 - 1938 (2007/10/02)

A study was carried out on the reaction of perfluorinated toluene, m-xylene, p-xylene, mesitylene, and m-(1-propenyl)toluene with inorganic oxides in the presence of antimony pentafluoride.Depending on the reaction conditions, polyfluorinated acids resulting from the consecutive conversion of trifluoromethyl groups into carboxylic acid groups are obtained after hydrolysis of the reaction mixtures.

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