52177-27-2

Basic information

• Product Name: Benzene, 5-ethoxy-1,3-dimethyl-2-nitro-
• Synonyms: Benzene,5-ethoxy-1,3-dimethyl-2-nitro
• CAS NO: 52177-27-2
• Molecular Formula: C10H13NO3
• Molecular Weight: 195.218
• Mol File: 52177-27-2.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 5-ethoxy-1,3-dimethyl-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 5-ethoxy-1,3-dimethyl-2-nitro-(52177-27-2)
• EPA Substance Registry System: Benzene, 5-ethoxy-1,3-dimethyl-2-nitro-(52177-27-2)

Safety Data

• Hazardous Substances Data: 52177-27-2(Hazardous Substances Data)

Upstream product

• 5344-97-8 3,5-dimethyl-4-nitrophenol 
• 75-03-6 ethyl iodide 
• 75-52-5 nitromethane 
• 457-23-8 2,6-Dimethyl-4-ethoxypyrylium tetrafluoroborate 

Downstream Products

• 54220-95-0 4-ethoxy-2,6-dimethylaniline 
• 14033-85-3 4-Amino-3,5-dimethylphenol hydrochloride 
• 527-61-7 2,6-dimethyl-1,4-benzoquinone 
• 5344-97-8 3,5-dimethyl-4-nitrophenol 

Relevant articles and documents

Amide derivative, preparation method of amide derivative, and application of amide derivative to pharmacy

The invention provides an amide derivative, a preparation method of the amide derivative, and application of the amide derivative to pharmacy. The amide derivative compound is selected from one of the following structures. The compound can be used for preparing medicines in the fields of local anaesthesia or analgesia. (The formulas are as shown in the description).

Direct Observation of the Cyclopropene-Vinylcarbene Rearrangement. Matrix Isolation of Bicyclohexa-3,5-dien-2-ones

4-Oxocyclohexa-2,5-dienylidenes 4b-g have been generated in argon matrices at 10 K by visible-light irradiation of the corresponding quinone diazides 5.Carbenes 4 have been characterized by IR and UV-vis spectroscopy and by their characteristic thermal reaction with molecular oxygen.On irradiation into the longest-wavelength absorption (420-700 nm), carbenes 4c-g rearrange to give the highly strained bicyclohexa-3,5-dien-2-ones 3c-g while 4b is photostable under the same conditions.The photochemical 4 -> 3 rearrangement is completely reversible: infrared irradiation or visible light irradiation (λ > 470 nm) of the cyclopropenes 3 lead back to triplet carbenes 4 quantitatively.In addition, several of the 1,3-bridged cyclopropenes 3 undergo a thermal rearrangement to give carbenes 4.This indicates that the highly strained cyclopropenes 3 are thermodynamically less stable than the corresponding carbenes 4 and kinetically only stabilized by a shallow energy barrier.Even under the conditions of matrix isolation at cryogenic temperatures, cyclopropenes 3 are metastable compounds.