52182-41-9

Usage

InChI:InChI=1/C15H10Cl2O/c16-13-7-5-12(6-8-13)15(18)9-4-11-2-1-3-14(17)10-11/h1-10H/b9-4+

Upstream product

• 99-91-2 para-chloroacetophenone 
• 587-04-2 m-Chlorobenzaldehyde 

Downstream Products

• 1042092-94-3 2-amino-7-(4-chlorophenyl)-5-(3-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one 
• 649739-67-3 2,3-dibromo-1-(4-chloro-phenyl)-3-(3-chloro-phenyl)-propan-1-one 
• 1499228-06-6 N-[4-(3-chlorophenyl)-6-(4-chlorophenyl)pyrimidine-2-yl]-4-methylbenzenesulphonamide 
• 1499228-04-4 N-[4-(2-chlorophenyl)-6-(4-chlorophenyl)pyrimidin-2-yl]-benzenesulphonamide 
• 1878-65-5 3-chlorophenylacetic acid 
• 74-11-3 para-chlorobenzoic acid 

Relevant academic research and scientific papers

Monitoring the DNA by ruthenium complexes of heterocyclic N,S-donor ligands and evaluation of biological activities

Neutral N,S-donor bidentate ligands have been synthesized and characterized by NMR and IR spectroscopic techniques. The ligands have been used to synthesized ruthenium(II) complexes ([Ru(L1–L6)PPh3)2Cl2/su

Synthesis, characterization of 4,6-disubstituted aminopyrimidines and their sulphonamide derivatives as anti-Amoebic agents

The present study describes the synthesis and anti-Amoebic activity of 4,6-disubstituted aminopyrimidines (1b-10b) and their sulphonamide derivatives (1-20). All the desired compounds were characterized by spectral data and their purity was confirmed by e

Synthesis and spectral analysis of novel 3-(4,6-diarylpyrimidin-2-yl)-2- phenylthiazolidin-4-ones

Novel 3-(4,6-diarylpyrimidin-2-yl)-2-phenylthiazolidin-4-ones are synthesized by the multicomponent cyclocondensation reaction of the appropriate 2-amino-4,6-diarylpyrimidines, benzaldehyde, and thioglycolic acid catalyzed by dicyclohexylcarbodiimide. The

Synthesis of some new cyanopyrans and cyanopyridines and their biological activities

Chalcones 1-aryl-3-m-chlorophenyl-2-propene-1-ones, 1a-j, underwent Michael addition on refluxing with malononitrile in the presence of pyridine and ammonium acetate in ethanol to give compounds 2-amino-3-cyano-4-(3′ -chlorophenyl),6-(4-phenyl)-pyran, 2a-

Synthesis and biological activities of some quinoxaline derivatives bearing aromatic halogen nucleus

1-Aryl-3-(3′-chlorophenyl)-2-propen-1-ones (1a-j) on reaction with bromine in acetic acid yielded 1-aryl-3-(3′ -chlorophenyl)-2,3-dibromopropan-1-ones (2a-j). Reaction of 2a-j with o-phenylenediamine afforded the corresponding 2-(3′ -chlorophenyl)-3-subst

Synthesis and biological activity of 3-aryl-5-(3′ -bromo/chlorophenyl)isoxazoles

3-Aryl-5-(3′-bromo/chlorophenyl)isoxazole derivatives (3a-j, 4a-j) have been prepared by condensing 1-aryl-3-(3′-bromo/ chlorophenyl)-2-propen-1-ones (1a-j, 2a-j) with hydroxylamine hydrochloride. Compounds 1a-j, 2a-j have been synthesized by the reaction

Multiple substituent effects on 13C chemical shifts in phenylstyryl ketones: Applicability of interactive free energy relationship

13C chemical shifts for 23 mono- and di-substituted phenyl styryl ketones have been determined. The shieldings and deshieldings are compared with previous results for other aromatic derivatives. Correlations of the 13C chemical shifts of vinyl carbons with Hammett σ parameters has been determined to provide a consistent picture of electronic effects transmitted through the carbon framework of the compounds studied. Slopes obtained from such Hammett's plots are termed as ρ, and using these 'ρ' values applicability of interactive free energy relationship to chemical shift values has been tested. The cross- interaction constants qx and qy values for C-α are found to be -1.02 and -1.20 and for C-β are -1.46 and -1.19.

Interactive free energy relationships for non-additive multiple substituent effects in base catalysed condensation of benzaldehydes with acetophenones: A kinetic study

The base-catalysed condensation of benzaldehydes with acetophenones is enhanced by electron-withdrawing substituents in both starting compounds.The magnitude of ρ-value obtained for various substituents in the benzaldehyde moiety decreases with the introduction of electron-withdrawing groups in the para position of acetophenone moiety.