52194-40-8

Upstream product

• 4192-77-2 ethyl cinnamate 
• 622-42-4 1-nitro-1-phenylmethane 
• 924-44-7 glyoxylic acid ethyl ester 
• 39090-78-3 ethyl 3-nitro-3-phenyl-2-hydroxycarboxylate 

Downstream Products

• 1038619-19-0 C₁₆H₂₂N₂O₄ 
• 706786-88-1 C₁₄H₁₅NO₄ 
• 1206899-31-1 ethyl 3-nitro-3-phenyl-2-(phthalimido)propanoate 

Relevant academic research and scientific papers

Addition of thionucleophiles to nitrocinnamates: Approach toward synthesis of (alkyl/aryl)thio-amino acids

The addition of alkyl or aryl thiols to α-nitro or β-nitrocinnamate in the presence of base provided Michael addition products. In the case of β-nitro compounds reaction occurred via the formation of anti-Michael adducts. Selective nitro reduction of α-ni

An unusual contra-Michael addition of NaNO2-ceric ammonium nitrate to acrylic esters

This report describes a novel regioselective contra-Michael addition to cinnamic esters that utilizes NaNO2-ceric ammonium nitrate.

NaNO2-ceric ammonium nitrate mediated conversion of acrylic esters and Baylis-Hillman derived acrylic esters into corresponding β-nitro acrylic esters

A variety of acrylic esters, including those derived from Baylis-Hillman reactions, react with NaNO2-ceric ammonium nitrate to form the corresponding β-nitro alcohols 2 and 5 whose dehydration, via their mesylates, leads to β-nitro acrylic esters, in good to excellent yields. Further, β-nitro acrylic esters containing a mesylate group 6, obtained from the Baylis-Hillman products, react with NaN3 to form 2-cyano-3-substituted acrylic esters 10 in excellent yields.