52196-76-6

Basic information

• Product Name: [2-(3,4-dimethoxyphenyl)-2-oxoethylidene]diazenium
• CAS NO: 52196-76-6
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 207.2054
• Mol File: 52196-76-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: [2-(3,4-dimethoxyphenyl)-2-oxoethylidene]diazenium(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(3,4-dimethoxyphenyl)-2-oxoethylidene]diazenium(52196-76-6)
• EPA Substance Registry System: [2-(3,4-dimethoxyphenyl)-2-oxoethylidene]diazenium(52196-76-6)

Safety Data

• Hazardous Substances Data: 52196-76-6(Hazardous Substances Data)

Usage

General Description

[2-(3,4-dimethoxyphenyl)-2-oxoethylidene]diazenium is a chemical compound with the molecular formula C10H12N2O5. It is a diazeniumdiolate, which is a type of organic compound containing a nitric oxide functional group. [2-(3,4-dimethoxyphenyl)-2-oxoethylidene]diazenium is an important intermediate in the synthesis of nitric oxide-releasing drugs, which are being studied for their potential therapeutic uses in various medical conditions. Nitric oxide-releasing compounds have been investigated for their potential as antimicrobial agents, vasodilators, and anti-inflammatory agents. The presence of the 3,4-dimethoxyphenyl group in this compound suggests that it may exhibit antioxidant and anti-inflammatory properties, although further research is needed to fully understand its biological effects.

Upstream product

• 93-07-2 Veratric acid 
• 52751-63-0 1,3-di-(3,4-dimethoxyphenyl)-1,3-propanedione 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 163428-90-8 2,2-dihydroxy-1-(3,4-dimethoxyphenyl)ethan-1-one 
• 186581-53-3 diazomethane 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 

Downstream Products

• 20931-30-0 2-(3,4-dimethoxy-phenyl)-3-hydroxy-5,7-dimethoxy-chromenylium; chloride 
• 7706-87-8 4-(3,4-dimethoxy-phenyl)-5H-furan-2-one 
• 37803-48-8 β-oxo-β-(3,4-dimethoxyphenyl)-ethanol 
• 10313-60-7 3,4-dimethoxyphenylacetyl chloride 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 20601-92-7 2-(3,4-dimethoxyphenyl)-2-oxoethyl chloride 
• 28891-68-1 1,2-Dibenzoyl-3-(3,4-dimethoxybenzoyl)-cyclopropan 
• 23808-78-8 (4-chloro-phenyl)-[3-(4-chloro-phenyl)-4-(3,4-dimethoxy-phenyl)-3H-thiazol-2-ylidene]-amine 
• 23808-79-9 (4-bromo-phenyl)-[3-(4-bromo-phenyl)-4-(3,4-dimethoxy-phenyl)-3H-thiazol-2-ylidene]-amine 
• 39561-76-7 α-acetoxy-3,4-dimethoxyacetophenone 
• 6924-15-8 2-amino-1-(3,4-dimethoxy-phenyl)-ethanol 

Relevant articles and documents

Practical Application of the Aqueous 'Sulfonyl-Azide-Free' (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters

The earlier described 'sulfonyl-Azide-free' ('SAFE') protocol for diazo transfer to CH-Acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a se

One-pot synthesis of polyfunctional pyrazoles: An easy access to α-diazoketones from arylglyoxal monohydrates and tosylhydrazine

A new and efficient method for the generation of α-diazoketones has been developed from arylglyoxal monohydrates and tosylhydrazine at room temperature. 1,3-Dipolar cycloaddition reactions were used to constructing polyfunctional pyrazole derivatives by the reaction of generated α-diazoketones in situ with electron-deficient alkenes, quinones and coumarins in one pot. The one-dimensional molecular packing of 1H-benzo[f]indazole-4,9-dione derivatives along the c direction demonstrated a helical chain formation via N-H?O hydrogen-bonding.

Potent and subtype-selective CCK-B/gastrin receptor antagonists: 2,4-dioxo-1,5-benzodiazepines with a plane of symmetry

A series of CCK-B/gastrin receptor antagonists, 2,4-dioxo-1,5-benzodiazepine derivatives with a plane of symmetry, were designed, synthesized, and evaluated for antagonistic activity. Structure-activity relationship studies revealed that carbonylmethyl groups at both N-1 and N-5 positions and hydrophilic groups, such as the carboxyl group on the benzene ring attached to the ureido group at the C-3 position, brought about potent affinity and subtype selectivity for CCK-B/gastrin receptors. Several compounds showed excellent in vivo inhibition of gastric acid secretion induced by pentagastrin in anesthetized rats.