52210-93-2 Usage
Uses
Used in Polymer Production:
2-(4-Allyloxy-phenoxymethyl)-oxirane is used as a monomer for the production of polymers, specifically epoxy resins. It contributes to the formation of these polymers due to its reactive oxirane group, which can undergo polymerization reactions.
Used in Adhesives and Coatings Industry:
In the adhesives and coatings industry, 2-(4-Allyloxy-phenoxymethyl)-oxirane is used as a crosslinking agent. Its ability to form covalent bonds with other molecules helps improve the strength and durability of adhesives and coatings.
Used in Specialty Chemicals Synthesis:
2-(4-Allyloxy-phenoxymethyl)-oxirane is also used as a modifier in the synthesis of specialty chemicals. Its unique structure allows it to be incorporated into various chemical formulations, enhancing their properties and performance.
Safety Note:
It is important to handle 2-(4-Allyloxy-phenoxymethyl)-oxirane with care, as it is considered a skin and respiratory irritant. Exposure to high concentrations can lead to adverse health effects, so proper safety measures should be taken during its use and storage.
Check Digit Verification of cas no
The CAS Registry Mumber 52210-93-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,2,1 and 0 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 52210-93:
(7*5)+(6*2)+(5*2)+(4*1)+(3*0)+(2*9)+(1*3)=82
82 % 10 = 2
So 52210-93-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O3/c1-2-7-13-10-3-5-11(6-4-10)14-8-12-9-15-12/h2-6,12H,1,7-9H2
52210-93-2Relevant academic research and scientific papers
Development of β-amino alcohol derivatives that inhibit toll-like receptor 4 mediated inflammatory response as potential antiseptics
Chavez, Sherry A.,Martinko, Alexander J.,Lau, Corinna,Pham, Michael N.,Cheng, Kui,Bevan, Douglas E.,Mollnes, Tom E.,Yin, Hang
, p. 4659 - 4669 (2011/09/15)
Toll-like receptor 4 (TLR4) induced proinflammatory signaling has been directly implicated in severe sepsis and represents an attractive therapeutic target. Herein, we report our investigations into the structure-activity relationship and preliminary drug metabolism/pharmacokinetics study of β-amino alcohol derivatives that inhibit the TLR4 signaling pathway. Lead compounds were identified from in vitro cellular examination with micromolar potency for their inhibitory effects on TLR4 signaling and subsequently assessed for their ability to suppress the TLR4-induced inflammatory response in an ex vivo whole blood model. In addition, the toxicology, specificity, solubility, brain-blood barrier permeability, and drug metabolism of several compounds were evaluated. Although further optimizations are needed, our findings lay the groundwork for the future drug development of this class of small molecule agents for the treatment of severe sepsis.
