52259-72-0

Basic information

• Product Name: 3,8,9-trimethoxybenzo[c]phenanthridin-2(5H)-one
• CAS NO: 52259-72-0
• Molecular Formula: C₂₀H₁₇NO₄
• Molecular Weight: 335.3533
• Mol File: 52259-72-0.mol

Chemical Properties

• Boiling Point: 786.3°C at 760 mmHg
• Flash Point: 429.4°C
• Density: 1.33g/cm³
• Vapor Pressure: 1.08E-24mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: 3,8,9-trimethoxybenzo[c]phenanthridin-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,8,9-trimethoxybenzo[c]phenanthridin-2(5H)-one(52259-72-0)
• EPA Substance Registry System: 3,8,9-trimethoxybenzo[c]phenanthridin-2(5H)-one(52259-72-0)

Safety Data

• Hazardous Substances Data: 52259-72-0(Hazardous Substances Data)

Upstream product

• 52259-71-9 O-isopropylnorfagaronine 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 1392399-35-7 3-(4-acetoxy-3-methoxyphenyl)-6,7-dimethoxy-4-(2-oxoethyl)isoquinoline 
• 1392399-31-3 3-(4-acetoxy-3-methoxyphenyl)-6,7-dimethoxy-4-(2-hydroxyethyl)isoquinoline 
• 98799-56-5 2-Isopropoxy-3,8,9-trimethoxy-11,12-dihydro-benzo[c]phenanthridine 
• 352545-29-0 N-acetyl-4,5-dimethoxy-2-iodobenzylamine 
• 98799-44-1 trans 4-(3-hydroxy-4-methoxyphenyl)but-3-enoic acid 
• 98799-33-8 2-iodo-4,5-dimethoxybenzylamine 
• 98799-45-2 6-isopropoxy-7-methoxy-1-tetralone 
• 5763-61-1 3,4-dimethoxybenzylamine 
• 98799-43-0 trans-4-(3,4-dimethoxyphenyl)but-3-enoic acid 
• 13575-75-2 6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydronaphthalene 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 15288-02-5 6-hydroxy-7-methoxy-1-tetralone 

Relevant articles and documents

Short synthesis and antimalarial activity of fagaronine

Herein, we report a new synthesis of fagaronine 1, inspired by the synthesis reported by Luo for nornitidine. The in vitro biological activity of fagaronine against malaria on several chloroquine-sensitive and resistant Plasmodium falciparum strains was c

Direct Synthesis of Benzophenanthridines and Benzophenanthridones via SRN1 Reactions

A straightforward and high-yield route to the 11,12-dihydrobenzophenanthridine (3) and 11,12-dihydrobenzophenanthridone (14) ring systems is based upon an SRN1 reaction between 2-halobenzylamines 1 or 2-halobenzoic acids 11 and enolates derived from tetralones 2.The efficient dehydrogenation of 3 or 14 gives the benzophenthridines 4 or benzophenanthridones 15.Use of properly substituted reactants leads to nitidine, avicine, and fagaronine and to analogues of those natural products.