52259-89-9Relevant academic research and scientific papers
Benzo[c]isothiazole 2-Oxides: Three-Dimensional Heterocycles with Cross-Coupling and Functionalization Potential
Lamers, Philip,Buglioni, Laura,Koschmieder, Steffen,Chatain, Nicolas,Bolm, Carsten
, p. 3649 - 3653 (2016)
A robust method for the synthesis of benzo[c]isothiazole 2-oxides has been developed providing a range of functionalized derivatives starting from anilines and DMSO. The reaction sequence can be performed on a gram scale and leads to products that can easily be modified by standard cross-coupling reactions. (Figure presented.).
