52287-50-0

Basic information

• Product Name: 1-(TRIMETHYLSILYL)-3,4-(METHYLENEDIOXY)BENZENE
• Synonyms: 1-(TRIMETHYLSILYL)-3,4-(METHYLENEDIOXY)BENZENE
• CAS NO: 52287-50-0
• Molecular Formula: C10H14O2Si
• Molecular Weight: 194.3
• Mol File: 52287-50-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(TRIMETHYLSILYL)-3,4-(METHYLENEDIOXY)BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(TRIMETHYLSILYL)-3,4-(METHYLENEDIOXY)BENZENE(52287-50-0)
• EPA Substance Registry System: 1-(TRIMETHYLSILYL)-3,4-(METHYLENEDIOXY)BENZENE(52287-50-0)

Safety Data

• Hazardous Substances Data: 52287-50-0(Hazardous Substances Data)

Usage

General Description

1-(Trimethylsilyl)-3,4-(methylenedioxy)benzene is a chemical compound with the formula C11H16O2Si. It is a derivative of benzene with a trimethylsilyl group attached to the 1-position and a methylenedioxy group attached to the 3 and 4-positions. 1-(TRIMETHYLSILYL)-3,4-(METHYLENEDIOXY)BENZENE has potential uses in organic synthesis, particularly as a building block for the preparation of complex molecules. It is also used in the development of pharmaceuticals and agrochemicals. It is important to handle this compound with caution, as it may be hazardous if not used properly.

Upstream product

• 2635-13-4 1,2-(methylenedioxy)-4-bromobenzene 
• 75-77-4 chloro-trimethyl-silane 
• 7228-38-8 5-chloro-1,3-benzodioxole 

Downstream Products

• 146853-20-5 5-Nitrosobenzo[d][1,3]dioxole 

Relevant articles and documents

Protodesilylation of Arylsilanes by Visible-Light Photocatalysis

The first visible-light-mediated photocatalytic, metal- and base-free protodesilylation of arylsilanes is presented. The C(sp2)-Si bond cleavage process is catalyzed by a 5 mol % loading of a commercially available acridinium salt upon blue-light irradiation. Two simple approaches have been identified employing either aerobic or hydrogen atom transfer cocatalytic conditions, which enable the efficient and selective desilylation of a broad variety of simple and complex arylsilanes under mild conditions.

Transition metal catalyzed preparation of Grignard compounds

The "inorganic Grignard reagents", in particular those of 1, have surprisingly been shown to be efficient homogeneous catalysts for the conversion of inactive chloroarenes and heteroarenes (via the aryl-iron intermediate 2) into the corresponding Grignard