52372-92-6Relevant articles and documents
Novel method for preparing thiophosphonate through oxidative dehydrogenation coupled reaction of copper-catalyzed diarylphosphine oxide and mercaptan
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Paragraph 0008; 0014-0015, (2020/12/14)
The invention provides a method for efficiently and highly selectively synthesizing thiophosphonate derivatives containing different substituted functional groups. According to the method, cuprous iodide is used as a catalyst, 2,2 '-dipyridyl is used as a ligand, pyridine is used as alkali, oxygen is used as an oxidizing agent, diarylphosphine oxide and a mercaptan compound are used as reaction substrates, and an organic solvent is added into a reaction system. The method has the advantages that the catalyst and the oxidant are cheap and easily available; substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of the obtained target product is close to 100%; and the yield of the target products is as high as 90% or above. The method overcomes the defects of poor reaction selectivity, complex reaction steps, low yield, need for reagents harmful to the environment and the like in traditional synthesis of thiophosphonate derivatives, and has goodindustrial application prospects. The invention also provides the corresponding thiophosphonate derivatives containing different substituted functional groups at the same time.
Studies on Organophosphorous Compounds XXXIII. Chemoselective Phase-Transfer Catalytic S-Alkylation of Dialkyl/diarylthiophosphinic Acids; A New Facile Route to S-Alkyl Dialkyl/diarylthiophosphinates
Yuan, Chengye,Feng, Hanzhen,Lin, Qiang
, p. 48 - 50 (2007/10/02)
A phase-transfer catalytic (PTC) alkylation involving the reaction of alkyl bromide and dialkyl/diarylthiophosphinic acids in the presence of potassium carbonate and tetrabutylammonium bromide is described.The reaction proceeds by SN2 mechanism
