14278-72-9Relevant articles and documents
Bismuth(iii) Thiophosphinates: Understanding How a Small Atomic Change Influences Antibacterial Activity and Mammalian Cell Viability
Senevirathna, Dimuthu C.,Duffin, Rebekah N.,Stephens, Liam J.,Herdman, Megan E.,Werrett, Melissa V.,Andrews, Philip C.
, p. 1226 - 1236 (2020/10/07)
Diphenylphosphinothioic acid (HSP(=O)Ph2) and diphenylphosphinodithioic acid (HSP(=S)Ph2) have been used to synthesise four BiIII complexes: 1 [Bi(SP(=O)Ph2)3], 2 [BiPh(SP(=O)Ph2)2], 3 [BiPh2(SP(=O)Ph2)], and 4 [Bi(SP(=S)Ph2)3], using BiPh3 and [Bi(OtBu)3] as bismuth sources. The complexes have been characterised by NMR spectroscopy, mass spectrometry, infrared spectroscopy, powder X-ray diffraction, and singe crystal X-ray crystallography (2-4). Biological studies indicated that despite complexes 2 and 3 reducing mammalian cell viability, their antibacterial activity provides a good degree of selectivity towards both Gram positive and Gram negative bacterial strains. The minimum inhibitory concentrations for complexes 2 and 3 are in the range of 0.52-5.5 μM towards the bacteria tested. Homoleptic complexes 1 and 4 were generally less active towards both bacterial and mammalian cells.
Acylation of Phosphorus-Substituted CH Acids under the Conditions of Phase-transfer Catalysis III. Acylation of Thiophosphinoylacetonitriles
Odinets,Artyushin,Kalyanova,Petrovskii,Lysenko,Antipin,Struchkov,Mastryukova,Kabachnik
, p. 43 - 53 (2007/10/03)
Acylation of thiophosphinoylacetonitriles under the conditions of phase-transfer catalysis involves the central carbon atom with formation of C-acyl derivatives in the enol form (Z-isomers) stabilized by intramolecular hydrogen bonding. Acylation with aromatic acyl halides also gives products of double C,O-acylation (Z-isomers), often predominating in amount. The yield of acylation products is affected by substituents at the phosphorus atom, the nature of acylating agent, and reaction conditions. The data of X-ray structural investigations of single crystals of (diphenylthiophosphinoyl)acetylacetonitrile enol and [isobutoxy(methyl)thiophosphinoylbenzoylacetonitrile enol benzoate are presented.
The reaction of α-amino-substituted diphenylphosphine oxide anions with elemental sulfur and selenium. A new route to thio- and selenoamides
Otten, P. A.,Gen, A. van der
, p. 499 - 506 (2007/10/02)
The lithiated anions of α-amino-substituted diphenylphosphine oxides 1, in which R can be hydrogen, aryl, alkyl and alkenyl, react with two equivalents of sulfur or selenium to form thio- and selenoamides, which can be isolated in good to excellent yields
