1518-72-5Relevant articles and documents
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Vineyard,B.D.
, p. 601 - 602 (1966)
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Zakharkin,L.I.,Gavrilenko,V.V.
, (1960)
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Gusarova et al.
, (1972)
Method for preparing disulfide bond containing compound by using TEMPO catalyst through aerobic oxidation
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Paragraph 0065; 0066; 0067; 0068; 0069; 0129-0132, (2016/10/07)
The invention discloses a method for preparing a disulfide bond containing compound by using a TEMPO catalyst through aerobic oxidation. The method comprises the following steps: adding R-SH, R'-SH and TEMPO into a solvent, and performing heating reflux in an aerobic environment, thereby preparing R-S-S-R'. The method achieves oxidative coupling reaction of thiophenol and mercaptan in the absence of transition metal and is high in yield, good in selectivity and free of over-oxidized product; for aliphatic mercaptan which is relatively poor in activity, the problem of oxidation can be solved by adding copper salt as a promoter, the yield is relatively high, and the reaction is greatly affected by a substitute group; the catalyst is easy to obtain, the reaction condition is gentle, and the method is applicable to large-scale production.
Methyl sulfinates as electrophiles in friedel-crafts reactions. Synthesis of aryl sulfoxides
Yuste, Francisco,Hernandez Linares, Angelica,Mastranzo, Virginia M.,Ortiz, Benjamin,Sanchez-Obregon, Ruben,Fraile, Alberto,Garcia Ruano, Jose Luis
scheme or table, p. 4635 - 4644 (2011/07/29)
The Friedel-Crafts reaction of methyl alkyl- and arylsulfinates with aromatic systems, activated by one or more electron-donating substituents (OH, OMe, NHR, NR2), provides alkyl aryl and diaryl sulfoxides under mild conditions and in moderate to good yields. The very high regioselectivity usually observed in these sulfinylation reactions is rationalized on the basis of a Wheland intermediate having a trigonal bypyramidal structure in which steric and electronic interactions are significant factors strongly destabilizing the attack to the ortho positions.