52395-25-2 Usage
Uses
Used in Pharmaceutical Industry:
5-(aminosulfonyl)-2-methoxybenzamide is used as a metabolite in the context of antipsychotic drug development for [application reason]. As a metabolite of Sulpiride, it may contribute to the drug's overall efficacy, safety profile, and pharmacological actions. Understanding the role of this metabolite can help in the optimization of antipsychotic medications and the development of new drugs with improved therapeutic properties.
Used in Research and Development:
5-(aminosulfonyl)-2-methoxybenzamide is used as a research compound for studying the metabolic pathways and pharmacological effects of antipsychotic drugs, particularly Sulpiride. This can aid in the development of new drugs with better efficacy and fewer side effects, as well as in understanding the mechanisms of action of existing antipsychotic medications.
Used in Drug Metabolism Studies:
5-(aminosulfonyl)-2-methoxybenzamide is used as a subject in drug metabolism studies to investigate how the body processes and eliminates antipsychotic medications. This information is crucial for determining the appropriate dosing regimens, understanding drug-drug interactions, and assessing the potential for adverse effects or toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 52395-25-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,3,9 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 52395-25:
(7*5)+(6*2)+(5*3)+(4*9)+(3*5)+(2*2)+(1*5)=122
122 % 10 = 2
So 52395-25-2 is a valid CAS Registry Number.
52395-25-2Relevant academic research and scientific papers
POTENTIAL NEUROLEPTICS OF THE ORTHOPRAMIDE SERIES; SYNTHESIS OF N-SUBSTITUTED 5-(AMINOSULFONYL)-2-METHOXYBENZAMIDES
Valenta, Vladimir,Protiva, Miroslav
, p. 2095 - 2106 (2007/10/02)
The mixed anhydride of 5-(aminosulfonyl)-2-methoxybenzoic acid (VII) and monoethyl carbonate reacted with benzylamine, 1-methylpiperazine, and 1-benzylpiperazine to give the 5-(aminosulfonyl)-2-methoxybenzamides II, IV, and V.Heating the ethyl ester X with 4-amino-1-methylpiperidine resulted in the amide III.Reaction of 5-(chlorosulfonyl)-2-methoxybenzoyl chloride (XI) with 1-benzylpiperazine afforded 5-(4-benzylpiperazinosulfonyl)-2-methoxybenzoic acid 4-benzylpiperazide (VI).Compounds II-VI are analogues of the antidopaminergic and antiemetic agent sulpiride (I) but only the benzylpiperazides V and VI showed indications of psychotropic activity of the neuroleptic type.
