5241-57-6

Upstream product

• 5241-58-7 L-Phenylalanine amide 
• 64-19-7 acetic acid 
• 3081-24-1 H-Phe-OEt 
• 5241-56-5 benzyl [(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamate 

Downstream Products

• 17337-80-3 3-Sulfo-Ala-Phe-amid 
• 5241-70-3 Z-D-Asp(OBzl)-Phe-NH₂ 
• 5549-49-5 Z-Asp(OBu^t)-Phe-NH₂ 
• 5241-68-9 Z-Asp(OBzl)-Phe-NH₂ 
• 17327-70-7 N-Benzyloxycarbonyl-S-benzyl-Cys-Phe-amid 

Relevant academic research and scientific papers

Process for lowering the viscosity of highly concentrated protein solutions

A process of lowering the viscosity of a solution includes preparing a solution comprising a compound of formula I, at a concentration in the final formulation of between 10 and 250 mM, and a protein having at least one antibody fragment whose concentration is between 50 and 350 mg/mL and whose pH is between 5 and 8. The compound lowers the viscosity of the solution, which is difficult to inject, by a value of at least 15% relative to the viscosity of a solution of at least one protein having at least one antibody fragment of the same concentration and of the same pH not containing the compound.