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52528-32-2

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52528-32-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 52528-32-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,5,2 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 52528-32:
(7*5)+(6*2)+(5*5)+(4*2)+(3*8)+(2*3)+(1*2)=112
112 % 10 = 2
So 52528-32-2 is a valid CAS Registry Number.

52528-32-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-benzylidene-6,6-dimethylbicyclo[3.1.1]heptan-4-one

1.2 Other means of identification

Product number -
Other names 6,6-dimethyl-3-(phenylmethylene)bicyclo[3.1.1]heptan-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52528-32-2 SDS

52528-32-2Relevant articles and documents

Design, synthesis and biological evaluation of novel β-pinene-based thiazole derivatives as potential anticancer agents via mitochondrial-mediated apoptosis pathway

Wang, Yunyun,Wu, Chenliang,Zhang, Qiangjian,Shan, Yu,Gu, Wen,Wang, Shifa

, p. 468 - 477 (2019/01/03)

A series of novel β-pinene-based thiazole derivatives were synthesized and characterized by HRMS, 1H NMR, and 13C NMR analyses as potential antineoplastic agents. Derivatives were evaluated for their anticancer activities in vitro, and the data manifested that most target compounds showed potent anti-proliferative activities against three human cancer cell lines. Especially, compound 5g displayed excellent cytotoxic activity against Hela, CT-26, and SMMC-7721 cell lines with IC50 values of 3.48 ± 0.14, 8.84 ± 0.16, and 6.69 ± 0.15 μM, respectively. To determine the underlying mechanism of compound 5g on cell viability, DAPI staining, Annexin-V/PI staining, JC-1 staining, DCFDA staining, and Western blot analysis were performed. Our data showed that compound 5g inhibited cell proliferation by inducing apoptosis and cell cycle arrest of Hela cells at the G0/G1 phase in a dose dependent manner. Further studies revealed that compound 5g enhanced levels of reactive oxygen species (ROS), caused a decrease in mitochondrial membrane potential, increased the release of mitochondrial cytochrome C, and affected the expression of Bax, Bcl-2, caspase-3 and caspase-9. Thus, our findings indicated that compound 5g induced apoptosis in Hela through ROS-mediated mitochondrial dysfunction signaling pathways.

four hydrogens kuikui zuo lin - 2 - amine sheaf alkali compound and its synthetic method and application

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Paragraph 0035; 0036; 0037; 0038, (2017/08/25)

The invention discloses tetrahydroquinazoline-2-schiff base compounds as well as a synthesis method and an application thereof. Novel tetrahydroquinazoline-2-schiff base compounds are prepared from a raw material of nopinone which is an oxidative product

Pinanyl pyrazole compound and its synthesis method and use

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Paragraph 0039; 0040, (2016/10/17)

The invention discloses a pinanyl pyrazole compound and its synthesis method and use. The synthesis method comprises that under action of base catalysis, nopinone and aromatic aldehyde undergo an aldol condensation reaction to produce 3-benzylidenenopinon

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