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Usage

Uses

Used in Organic Synthesis:
(2E)-3-(4-chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one is utilized as a reagent and intermediate in the synthesis of various organic compounds, leveraging its unique structural features to facilitate chemical reactions and the formation of desired products.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (2E)-3-(4-chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one is employed as a compound of interest for research and development. Its potential biological activities and therapeutic properties are being studied, which may lead to the discovery of new drugs and treatments.
Used in Agrochemical Industries:
(2E)-3-(4-chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one also holds promise in agrochemical applications due to its unique structural features. It may be used in the development of new agrochemical products, contributing to advancements in agriculture and pest control.

Upstream product

• 7228-47-9 2-(2-naphthyl)ethanol 
• 104-88-1 4-chlorobenzaldehyde 
• 93-08-3 methyl 2-naphthyl ketone 

Downstream Products

• 113341-15-4 3-(4-Chloro-phenyl)-5-naphthalen-2-yl-2-naphthalen-1-yl-5-oxo-pentanenitrile 
• 113341-16-5 3-(4-Chloro-phenyl)-2-(2,6-dichloro-phenyl)-5-naphthalen-2-yl-5-oxo-pentanenitrile 
• 127612-51-5 4-carboethoxy-3,5-di(4-chlorophenyl)-4-cyano-2-(2-naphthoyl)-1-(2-naphthyl)cyclohexanol 
• 127394-71-2 4-(4-Chloro-phenyl)-2-ethoxy-6-naphthalen-2-yl-nicotinonitrile 
• 113341-17-6 2,3-Bis-(4-chloro-phenyl)-5-naphthalen-2-yl-5-oxo-pentanenitrile 
• 114346-67-7 5-(4-chlorophenyl)-3-(2-naphthyl)-1-phenyl-2-pyrazoline 
• 1133717-13-1 C₂₀H₁₅NO₃ 
• 1260620-98-1 4-(4-chlorophenyl)-3-methyl-6-(naphthalen-2-yl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 438230-07-0 4-(4-chlorophenyl)-6-(naphthalen-2-yl)pyrimidin-2-amine 
• 1276692-07-9 4-(4-chlorophenyl)-4,5-dihydro-6-(naphthalen-2-yl)-2H-indazol-3-ol 
• 114039-90-6 ethyl 6-(4-chlorophenyl)-4-(naphthalen-2-yl)-2-oxocyclohex-3-enecarboxylate 
• 1438279-06-1 (S)-3-(4-chlorophenyl)-3-(1H-indol-3-yl)-1-(naphthalen-2-yl)propan-1-one 
• 126934-49-4 naphthalen-2-yl-3-(4-chlorophenyl)oxiran-2-yl-methanone 

Relevant academic research and scientific papers

Synthesis, Biological Activity and Action Mechanism Study of Novel Chalcone Derivatives Containing Malonate

A series of novel chalcone malonate derivatives were synthesized and their antibacterial and antiviral activities were evaluated. All target compounds were characterized by spectral data. The results of antimicrobial bioassay showed that one compound (die

Aldol condensations of a variety of different aldehydes and ketones under ultrasonic irradiation using poly(N-vinylimidazole) as a new heterogeneous base catalyst under solvent-free conditions in a liquid-solid system

An ultrasound-assisted aldol condensation reaction has been developed for a range of ketones with a variety of aromatic aldehydes using poly(N-vinylimidazole) as a solid base catalyst in a liquid-solid system. The catalyst can be recovered by simple filtration and reused at least 10 times without any significant reduction in its activity. The reaction is also amenable to the large scale, making the procedure potentially useful for industrial applications.

Synthesis and antimicrobial activities of new 4,6-diaryl- 4,5-dihydro-3-hydroxy-2H-indazoles

A series of new 4,6-diaryl-4,5-dihydro-3-hydroxy-2H-indazoles 5a-5k were synthesized by the cyclization of ethyl 2-oxo-4,6-diarylcyclohex-3-ene carboxylates 4a-4k. The compounds were characterized by IR, 1H NMR, 13C NMR, 2D NMR, and elemental analysis. The synthesized compounds were evaluated for in vitro antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Salmonella typhimurium, Pseudomonas aeruginosa, Candida albicans, Aspergillus niger, Aspergillus flavus, and Rhizopus sp. Most of the compounds exhibited good activity against the tested organisms. Copyright

Anti-bacterial and anti-leishmanial studies of 4, 6-diarylpyrimidin-2- amines

Seven new chalcones along with nine already reported ones were synthesized from aryl aldehydes and substituted acetophenones by Claisen-Schmidt condensation. Each chalcone was treated with guanidine hydrochloride followed by oxidation with H2O

Atom-efficient, solvent-free, green synthesis of chalcones by grinding

An improved Claisen-Schmidt condensation reaction of methyl ketones and aromatic aldehydes can be achieved by grinding at room temperature in the absence of solvents. This process is simple, efficient, economical, and environmentally benign compared to classical reactions.

Microwave-assisted synthesis of some 3,5-arylated 2-pyrazolines

Condensation of 2-acetylnaphthalene with benzaldehydes under microwave irradiation affords chalcones which undergo facile and clean cyclizations with hydrazines RNHNH2 (R= H, Ph, Ac) to afford 3,5-arylated 2-pyrazolines in quantitative yields,

Solvent-free crossed aldol condensation of ketones with aromatic aldehydes mediated by magnesium hydrogensulfate

Crossed aldol condensations of ketones with aromatic aldehydes are carried out efficiently in the presence of magnesium hydrogensulfate under solvent-free conditions in good to excellent yield without the occurrence of any self-condensation. Similar reactions in solution do not proceed satisfactorily.