52604-30-5Relevant articles and documents
Nanosilica molybdic acid: synthesis, characterization and application as a green and reusable catalyst for the Pechmann condensation
Kiani, Mahtab,Karami, Bahador
, p. 655 - 663 (2017/01/17)
Abstract: Nanosilica molybdic acid (SMA NPs) was founded as an efficient and recyclable nanocatalyst for the synthesis of coumarin derivatives in excellent yields with good purity. Nano-SMA as a new solid acid was characterized by X-ray fluorescence, X-ray diffraction, energy-dispersive X-ray analyzer, transmission electron microscopy and Fourier transform infrared spectroscopy. Coumarin derivatives were obtained via the Pechmann condensation reaction of phenols and β-ketoesters at 80?°C under solvent-free conditions. The main advantages of the present procedure are high yields, shorter reaction time and green chemistry procedure, simple work-up and inexpensive and reusability of the catalyst. Graphical Abstract: [Figure not available: see fulltext.]
Environmentally sustainable magnetic solid sulfonic acid: An efficient and reusable catalyst for the Pechmann reaction
Mobaraki, Akbar,Yasham, Shahriar,Movassagh, Barahman
supporting information, p. 1263 - 1268 (2015/06/02)
Abstract An environmentally benign sulfonic acid nanocomposite based on Fe3O4@SiO2 core-shell magnetic nanoparticles, Fe3O4@SiO2@Et-PhSO3H, was prepared and the acidity and utility of the catalyst were explored for the synthesis of a diverse range of coumarin derivatives under solvent-free conditions. The catalyst shows potential for scale up in the synthesis of coumarins with high purity and was easily separated by using an external magnet. The recovered catalyst was reused in seven cycles without any significant loss of activity.
ZrOCl2.8H2O/SiO2: An efficient and recyclable catalyst for the preparation of coumarin derivatives by Pechmann condensation reaction
Karami, Bahador,Kiani, Mahtab
experimental part, p. 62 - 67 (2012/01/15)
Silica gel supported zirconyl chloride octahydrate was found to be an efficient and recyclable catalyst for the synthesis of a series of biologically important molecules in high turnover numbers and rates. Several substituted coumarins can be prepared in high yield and purity by direct reaction of β-keto esters and phenol derivatives in the presence of a catalytic amount of ZrOCl2.8H2O/SiO2 as Lewis acid and at ambient temperature under solvent-free conditions. This method which is called Pechmann condensation is a very easy and a rapid reaction for the synthesis of coumarin derivatives.