52612-54-1Relevant articles and documents
Discovery of Antimetastatic Chiral Ionone Alkaloid Derivatives Targeting HIF-1α/VEGF/VEGFR2 Pathway
Liu, Jing-Jing,Liu, Xin-Yao,Nie, Jiang-Ping,Jia, Mei-Qi,Yu, Yang,Qin, Nan,Duan, Hong-Quan
, p. 2130 - 2145 (2021)
Novel chiral ionone alkaloid derivatives were synthesized and their antimetastatic effects were evaluated in human breast cancer cells using chemotaxis assay. Compared with positive control LY294002, a PI3 K inhibitor, derivatives 10 a, 11 a, 11 c, 11 g,
Synthesis and anti-metastatic effects of novel chiral ionone alkaloid derivatives
Fang, Hai-Jun,Shou, Xiao-Ai,Liu, Qian,Gan, Chun-Chun,Duan, Hong-Quan,Qin, Nan
, p. 245 - 253 (2015/07/08)
Abstract Novel chiral ionone alkaloid derivatives were synthesized and evaluated their anti-metastatic effects in human MDA-MB-231 breast cancer cells. The chiral center C-6 of derivatives exerted an important role in response to the anti-metastatic activ