83059-15-8

Upstream product

• 52612-54-1 (+)-(R)-3-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-(E)-propensaeure 
• 24190-29-2 (R)-α-ionone 
• 341497-26-5 (R)-4,4-dimethyl-2-iodo-2-cyclohexen-1-ol 
• 157952-85-7 2-iodo-4,4-dimethyl-cyclohex-2-enone 
• 52567-56-3 (-)-α-Cyclogeranylethanol 
• 1073-13-8 4,4-dimethylcyclohexenone 
• 147379-73-5 (3)-<(R)-2,6,6-trimethl-2-cyclohexenyl>propanal 
• 83059-14-7 (+)-(R)-3-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-(E)-propenol 
• 725739-83-3 phosphoric acid diethyl ester (R)-2-iodo-4,4-dimethylcyclohex-2-enyl ester 
• 725740-03-4 ethyl 3-(2,6,6-trimethylcyclohex-2-en-1-yl)propanoate 
• 725739-97-9 (R)-3-(2-iodo-6,6-dimethylcyclohex-2-enyl)propionic acid ethyl ester 

Downstream Products

• 83021-19-6 (+)-(R)-9-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-(all-E)-2,4,6,8-nonatetraen-1-ol 
• 83021-20-9 (+)-(R)-9-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-(all-E)-2,4,6,8-nonatetraenal 
• 24190-29-2 (R)-α-ionone 
• 472-78-6 α-ionol 
• 83021-18-5 (+)-(R)-9-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-(all-E)-2,4,6,8-nonatetraensaeureaethylester 

Relevant academic research and scientific papers

Enantioselective synthesis of α-ionone derivatives using an anti SN2′ substitution of functionalized zinc organometallics

(Equation Presented) The allylic substitution of sterically hindered (2-iodocycloalkyl)phosphates proceeds with complete anti SN2′ stereoselectivity with mixed diorganozincs of the type RZnCH 2SiMe3 in the presence of CuCN·2LiCI. Only the group R of the copper-zinc reagent is transferred in the allylic substitution. This method was used to prepare odoriferous substances such as (R)-α-ionone in 97% ee and (R)-dihydro-α-ionone in 98% ee.