52629-60-4

Usage

Classification

Chemical compound
Derivative of silyl enol ether

Usage

Reagent in organic synthesis reactions
Important building block in organic chemistry

Functionality

Ability to substitute an alpha hydrogen atom in carbonyl compounds
Valuable tool for the formation of new carbon-carbon bonds

Application

Preparation of highly functionalized molecules and pharmaceutical compounds

Upstream product

• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 789-25-3 HSiPh₃ 
• 18666-68-7 vinyltriphenylsilane 
• 61979-36-0 (1,2-dibromoethyl)triphenylsilane 
• 18676-45-4 α-bromovinyltriphenylsilane 
• 100-52-7 benzaldehyde 

Downstream Products

• 49750-05-2 phenyl 1-(triphenylsilyl)vinyl ketone 
• 52629-66-0 1-Trifluoracetoxy-1-phenyl-2-triphenylsilyl-2-propen 
• 65071-63-8 (Z)-1-Phenyl-2-triphenylsilyl-3-chlor-1-propen 
• 52629-67-1 2-Triphenylsilyl-3-chlor-3-phenyl-1-propen 

Relevant academic research and scientific papers

Copper(I) tert-butoxide-promoted allylation of β-triphenylsilyl allylic alcohols via 1,3 Csp2-to-o silyl migration

The substitution of the silyl group in vinylsilanes by an allylic group proceeded when β-triphenylsilylallyl alcohols were treated with copper(I) tert-butoxide and allylic halides. This reaction is the first synthetic application of 1,3 Csp2-to-O silyl migration which provides a useful method for generation of vinyl anion equivalents.

Highly stereoselective and efficient hydrosilylation of terminal alkynes catalyzed by [RuCl2(p-cymene)]2

(Formula presented) With [RuCl2(p-cymene)]2 as a catalyst, extremely high regio-and stereoselectivity was observed in the hydrosilylation reaction of various terminal alkynes under mild conditions to afford β-(Z)-vinylsilanes in exce