52670-78-7

Upstream product

• 814-49-3 diethyl chlorophosphate 
• 100-61-8 N-methylaniline 
• 2397-47-9 triethyl N-phenylphosphorimidate 
• 74-88-4 methyl iodide 
• 122-52-1 triethyl phosphite 
• 762-04-9 phosphonic acid diethyl ester 
• 64-17-5 ethanol 
• 2503-67-5 methyl-phenyl-amidophosphoryl chloride 
• 141-52-6 sodium ethanolate 

Downstream Products

• 115384-36-6 diethyl <2-(methylamino)phenyl>phosphonate 

Relevant academic research and scientific papers

Electrochemical phosphorylation of arenols and anilines leading to organophosphates and phosphoramidates

A practical phosphorylation for generating organophosphates and phosphoramidatesviaelectrochemical dehydrogenative cross-coupling of P(O)H compounds with arenols and anilines is disclosed. This method involves using inorganic iodide salts as both redox catalysts and electrolytes in an undivided cell without the addition of oxidants or bases. A preliminary mechanistic study suggests that radicals are not involved in this process. This method is green and eco-friendly and has good functional group tolerance, high yields and broad substrate scope, with the potential for practical synthesis.

Trichloroisocyanuric Acid as an Efficient Reagent for the Synthesis of Phosphoroamidates via Atherton-Todd Reaction under Base-Free Conditions

A simple, efficient, and novel method is developed for the synthesis of phosphoroamidates via an Atherton-Todd coupling reaction of amines with dialkyl H-phosphite using trichloroisocyanuric acid as an efficient and safe reagent. Treatment of amines with dialkyl H-phosphite and trichloroisocyanuric acid under base-free conditions gives phosphoroamidates in moderate to good yields. The reaction proceeded effectively to afford the corresponding phosphoroamidates via a dehydrogenative coupling of H-phosphonates with amines. This method is easy, rapid, and good-yielding for the synthesis of phosphoroamidates.

Fe3O4@MgO nanoparticles as an efficient recyclable catalyst for the synthesis of phosphoroamidates via the Atherton-Todd reaction Dedicated to Professor Tsutomu Yokomatsu from Tokyo University of Pharmacy and Life Sciences on the occasion of his 65th birthday

A simple and efficient method is presented for the synthesis of phosphoroamidates in moderate to good yield via the Atherton-Todd coupling of primary amines with H-dialkyl phosphites using Fe3O4@MgO nanoparticles as a recyclable catalyst.

Cross-hetero-dehydrogenative coupling reaction of phosphites: A catalytic metal-free phosphorylation of amines and alcohols

Phosphorylation of amines, alcohols, and sulfoximines are accomplished using molecular iodine as a catalyst and H2O2 as the sole oxidant under mild reaction conditions. This method provides an easy route for synthesizing a variety of phosphoramidates, phosphorus triesters and sulfoximine-derived phosphoramidates which are of biological importance.

In the manufacture of pulp waste newspaper deinkable derived

PROBLEM TO BE SOLVED: To recover ashes containing a filler in a good yield from a pulp slurry originated from waste newspaper. SOLUTION: This method for producing deinked pulp originated from waste newspaper, including adding an additive for producing the deinked pulp to a pulp slurry originated from the waste newspaper on a deinking treatment, is characterized by adding an additive for producing the deinked pulp to the pulp slurry after a flotation process and before a process for dehydrating the pulp slurry, wherein the additive is a combination of (A) a substance for converting a water-soluble silicate into a slightly soluble silicate with (B) a water-soluble polymer; (A) the substance is selected from inorganic acids, 1 to 4C organic acids, polyvalent metal salts, polyvalent metal hydroxides, polyvalent metal salt condensation products, and the like; and (B) the water-soluble polymer is selected from amphoteric polymers, cationic polymers, and anionic polymers. Thus, atomized or dissolved silicate-based fillers much contained in the deinked pulp originated from the waste newspaper are again converted into insoluble substances with the component (A), and the insoluble substances are smoothly coagulated with the component (B). Therefore, the ashes containing the fillers can be recovered in a good yield. COPYRIGHT: (C)2007,JPOandINPIT

DIREKTSYNTHESE VON N,N-DIORGANYL-PHOSPHORSAEUREDIALKYLESTERAMIDEN AUS TRIALKYLPHOSPHITEN

Dialkyl N,N-Diorganylphosphoroamidates result in the reaction of trialkylphosphites with secondary amines and tetrachlormethane if amine hydrochlorides are used as catalysts.A reaction mechanism is proposed.Key words: N,N-Diorganylphosphoroamidates; trialkylphosphites; tetrachlormethane.

Metalation-Induced-Migration of Phosphorus from Nitrogen to Carbon

Phosphoric N-phenylamides undergo lithiation-induced rearrangement involving the fission of the P-N bond and the migration of phosphorus to the ortho aromatic carbon atom.In the O-phenyl N-phenylamido esters the migration to the phenolic ring preceeds tha