52708-03-9Relevant articles and documents
The Solvent Effects on the Optical Rotatory Properties of 1,7-Diaryl-5-hydroxy-3-heptanones and Related Compounds
Ohta, Shinji
, p. 1181 - 1188 (1986)
The ORD and CD curves of (S)-1,7-diphenyl-5-hydroxy-3-heptanone, (S)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxy-3-heptanone, and related model compounds were obtained in selected solvents with different polarity.Causing the 1,7-diaryl-5-hydroxy-3-heptanones d
Titanocene-catalyzed regiodivergent epoxide openings
Gansaeuer, Andreas,Fan, Chun-An,Keller, Florian,Keil, Jutta
, p. 3484 - 3485 (2008/01/01)
The first regiodivergent opening of unbiased epoxides providing the ring-opened products in high enantiomeric excess from racemic and exceptionally high enantiomeric excess from enantioenriched substrates in a double asymmetric process has been devised. It constitutes a more general case of the very important enantioselective openings of meso-epoxides. Copyright
Chemoenzymatic synthesis of α-halogeno-3-octanol and 4- or 5-nonanols. Application to the preparation of chiral epoxides
Besse, Pascale,Sokoltchik, Tania,Veschambre, Henri
, p. 4441 - 4457 (2007/10/03)
A study of the microbiological reduction of different α- halogenoketones (4-chloro-3-octanone, 4-chloro-5-nonanone, 5-bromo-4-nonanone and 5-chloro-4-nonanone) with several strains of microorganism showed great difficulty in reducing ketone functions located in the middle of carbon chains. However, by choosing the appropriate microorganism, several enantiomerically pure diastereoisomers of the corresponding halohydrins have been obtained and were transformed into chiral epoxides.
ASYMMETRIC SYNTHESIS VIA CHIRAL SILICON REAGENTS. CHIRAL α-HYDROXYALKYL ANION EQUIVALENTS FROM VINYLSILANES CONTAINING OPTICALLY ACTIVE AMINO OR ALKOXY GROUPS ON SILICON
Tamao, Kohei,Kanatani, Ryuichiro,Kumada, Makoto
, p. 1913 - 1916 (2007/10/02)
Chiral vinylsilanes containing optically active functional groups on silicon have been used as precursors for chiral α-hydroxyalkyl anion equivalents via a sequence of addition of n-butyllithium, coupling with organic halides, and oxidative cleavage of the silicon-carbon bond, to give optically active alcohols of up to 60percent ee.