5273-61-0

Usage

Uses

Used in Organic Synthesis:
5,6-dibromocyclohex-2-ene-1,4-dione is used as a building block in organic synthesis for the creation of various chemical compounds. Its unique structure and reactivity make it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
5,6-dibromocyclohex-2-ene-1,4-dione is used as an intermediate in the production of pharmaceuticals. Its strong oxidizing properties and ability to react with a wide range of organic compounds contribute to the development of new and effective drugs.
Used in Agrochemical Production:
5,6-dibromocyclohex-2-ene-1,4-dione is used as an intermediate in the production of agrochemicals. Its versatility in organic synthesis allows for the creation of new and improved agrochemicals for agricultural applications.
Used in Fine Chemical Production:
5,6-dibromocyclohex-2-ene-1,4-dione is used as an intermediate in the production of fine chemicals. Its unique properties and reactivity make it a valuable component in the synthesis of high-quality specialty chemicals.
Used as a Reagent in Organic Compound Preparation:
5,6-dibromocyclohex-2-ene-1,4-dione is used as a reagent in the preparation of other organic compounds. Its strong oxidizing properties enable it to participate in various chemical reactions, contributing to the synthesis of a wide range of organic compounds.

InChI:InChI=1/C6H4Br2O2/c7-5-3(9)1-2-4(10)6(5)8/h1-2,5-6H

Upstream product

• 106-51-4 p-benzoquinone 
• 169529-93-5 (-)-2,3-dibromocyclohex-5-ene-1,4-diol 
• 69945-44-4 (1RS,2SR,3RS,4RS)-2,3-dibromocyclohex-5-ene-1,4-diol 
• 7726-95-6 bromine 

Downstream Products

• 105143-22-4 2,5-bis-[(2-hydroxy-ethyl)-methyl-amino]-[1,4]benzoquinone 
• 99057-79-1 2-[bis-(2-chloro-ethyl)-amino]-5-bromo-[1,4]benzoquinone 
• 3958-82-5 2-bromo-1,4-benzoquinone 
• 123-31-9 hydroquinone 
• 10035-10-6 hydrogen bromide 
• 13070-31-0 2,5,6-tribromocyclohex-2-ene-1,4-dione 
• 80582-75-8 (1R,2R,3R,4R)-anti-benzene dioxide 
• 169529-92-4 (+)-(1R,2S,3S,4R)-2,3-dibromocyclohex-5-ene-1,4-diol 
• 112212-81-4 (+/-)-(1S,2R,3R,4S)-1,4-diacetoxy-2,3-dibromocyclohex-5-ene 
• 112791-61-4 [3H]-Inositol-3,4,5,6-tetrakisphosphate 
• 170210-89-6 (+)-(1S,2R,3R,4S)-1,4-diacetoxy-2,3-dibromocyclohex-5-ene 
• 1311140-98-3 Inositol 1,5,6-triphosphate 
• 222420-77-1 (1S,2R,3R,4S)-1,4-bis-O-(di-O-benzylphospho)conduritol B 
• 864372-82-7 (1S,2S,3S,4S)-1,4-bis-O-(di-O-benzylphospho)-2,3-bis-O-(2-oxo-5,6-benzo-1,3,2-dioxaphosphep-2-yl)conduritol-B 

Relevant academic research and scientific papers

Concise syntheses and some biological activities of dl-2,5-di-O-methyl-chiro-inositol, dl-1,4-di-O-methyl-scyllo-inositol, and dl-1,6-dibromo-1,6-dideoxy-2,5-di-O-methyl-chiro-inositol

The regio- and stereospecific synthesis of O-methyl-chiro-inositols and O-methyl-scyllo-inositol was achieved, starting from p-benzoquinone. After preparing dimethoxy conduritol-B as a key compound, regiospecific bromination of the alkene moiety of dimeth

Regio- and stereospecific synthesis of DL-4,5-dibromo-4,5-dideoxy-3,6-O-methyl-chiro-inositol

The regio- and stereospecific synthesis of DL-4,5-dibromo-4,5-dideoxy-3,6-O-methyl-chiro-inositol is reported. Bromination of p-benzoquinone followed by reduction of the carbonyl groups with NaBH4 gave the corresponding trans-dibromodiol compou

LADDERANE LIPID COMPOUNDS AND LIPOSOMES AND METHODS OF PREPARING AND USING THE SAME

Methods for preparing a variety of ladderane precursors, ladderane compounds and ladderane lipids are provided. Also provided are methods of preparing a liposome from the ladderane lipids disclosed herein, and compositions thereof. Aspects of the invention include encapsulated one or more cargo moieties in the liposome or compositions thereof and use of the subject liposome compositions as vehicles in drug delivery, imaging, diagnostics and other medical applications. Aspects of the methods disclosed herein include administering a liposomal composition comprising a pharmaceutical agent to a subject under conditions sufficient to deliver the composition to a site of interest in the subject, and release the pharmaceutical agent from the liposomal composition.

Chemical Synthesis and Self-Assembly of a Ladderane Phospholipid

Ladderane lipids produced by anammox bacteria constitute some of the most structurally fascinating yet poorly studied molecules among biological membrane lipids. Slow growth of the producing organism and the inherent difficulty of purifying complex lipid mixtures have prohibited isolation of useful amounts of natural ladderane lipids. We have devised a highly selective total synthesis of ladderane lipid tails and a full phosphatidylcholine to enable biophysical studies on chemically homogeneous samples of these molecules. Additionally, we report the first proof of absolute configuration of a natural ladderane.

Synthesis of novel mono and bis-indole conduritol derivatives and their α/β-glycosidase inhibitory effects

Here we synthesized four novel indole conduritol derivatives 1-4 for the first time in the literature and probed their biological activities with the α and β-glucosidases. The compounds showed quite effective glucosidase inhibitory action. IC50

Synthesis of novel cyano-cyclitols and their stereoselective biotransformation catalyzed by Rhodococcus erythropolis A4

A variety of novel cyano-cyclitols possessing complex stereochemistry have been synthesized. These compounds were subjected to the biocatalyzed hydrolysis of their nitrile groups. The bacterial strain Rhodococcus erythropolis A4, expressing a nitrile hydr

A novel chemo-multienzymatic synthesis of bioactive cyclophellitol and epi-cyclophellitol in both enantiopure forms

A new route to synthesize cyclophellitol and epi-cyclophellitol from racemic starting materials in enantiopure forms has been developed. The synthesis involves a multi-enzymatic biotransformation pathway of the novel cyano-cyclitol (1R,4S,5R,6R)/(1S,4R,5S

Asymmetric induction of conduritols via AAA reactions: Synthesis of the aminocyclohexitol of hygromycin A

Two synthetic routes towards the construction of the aminocyclohexitol moiety of hygromycin A have been developed based on palladium-catalyzed asymmetric alkylation of conduritol derivatives. A protocol has been established whereby this biologically relev

Enzyme-assisted total synthesis of the optical antipodes D-myo-inositol 3,4,5-trisphosphate and D-myo-inositol 1,5,6-trisphosphate: Aspects of their structure-activity relationship to biologically active inositol phosphates

Unambiguous total syntheses of both optical antipodes of the enantiomeric pair D-myo-inositol 3,4,5-trisphosphate (Ins(3,4,5)P3) and D- myo-inositol 1,5,6-trisphosphate (Ins(1,5,6)P3) are described. The ring system characteristic of

Enantioselective synthesis of (-)-LL-C10037α from benzoquinone

(formula presented) The enantioselective total synthesis of the Streptomyces metabolite (-)-LL-C10037α has been accomplished in 10 steps and 20% overall yield. An early chiral intermediate was resolved with Candida rugosa lipase to provide (+)-5 with an e