52764-11-1Relevant academic research and scientific papers
TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
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Paragraph 0223, (2014/08/07)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
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Page/Page column 27, (2013/03/26)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
TETRACYCLIC HETEROCYCLE COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES
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Page/Page column 32-33, (2013/03/26)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
Efficient synthesis of halohydroxypyridines by hydroxydeboronation
Voisin, Anne Sophie,Bouillon, Alexandre,Lancelot, Jean-Charles,Rault, Sylvain
, p. 1417 - 1421 (2007/10/03)
This paper describes a general method for the synthesis of halohydroxypyridines from novel halopyridinylboronic acids and esters recently described by some of us. Halopyridinylboronic acids and esters have been efficiently hydroxydeboronated under mild conditions by employing hydrogen peroxide or meta-chloroperbenzoic acid. These hydroxylations take place regioselectively without other oxidation (N-oxide formation).
Certain esters of 2-[(2,6-dichloro-3-pyridyl)oxy]propionic acid, compositions containing same and their herbicidal properties
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, (2008/06/13)
This invention relates to 3-pyridinol compounds corresponding to formula I STR1 wherein A is halogen, alkyl or cyano B is halogen Q is an aliphatic bridge that can also be unsaturated, branched or substituted R is hydrogen, an aliphatic, cycloaliphatic, aromatic or heterocyclic radical, a metal ion or a quaternary ammonium group, Z is oxygen or sulfur, processes for producing them, their use for regulating plant growth, and to compositions containing these compounds.
3-Pyridyl-oxy-alkanecarboxylic acid amides
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, (2008/06/13)
The present invention relates to 3-pyridyl-oxy-alkancarboxylic acid amides of formula STR1 wherein A and B are individually hydrogen, halogen, alkyl, cyano, nitro or amino, C is hydrogen, halogen or nitro n is 1 or 2 Q is an aliphatic bridge, that can also be branched, unsaturated or substituted, R1 and R2 independently are hydrogen, alkyl, alkoxy, alkenyl, alkynyl, phenyl or benzyl, R1 and R2 together with the nitrogen atom to which they are bound are a 5 to 6 membered heterocycle. The invention also relates to processes for the production of these amides, to their use as regulators of plant growth and as antidotes for herbicides, as well as to compositions containing these amides as active substance.
