527751-18-4

Basic information

• Product Name: Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)
• Synonyms: Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI);(1S,3R)-3-Amino-2,2-dimethylcyclobutanecarboxylic acid;(1S, 3R)-3-Amino-2,2-dimethylcyclobutane-1-carboxylic acid hydrochloride
• CAS NO: 527751-18-4
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.18362
• Product Categories: AMINOACID
• Mol File: 527751-18-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 245.4±33.0 °C(Predicted)
• Appearance: /
• Density: 1.108±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.69±0.40(Predicted)
• CAS DataBase Reference: Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)(527751-18-4)
• EPA Substance Registry System: Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)(527751-18-4)

Safety Data

• Hazardous Substances Data: 527751-18-4(Hazardous Substances Data)

Upstream product

• 188918-44-7 tert-butyl [(1R,3S)-3-acetyl-2,2-dimethylcyclobutyl]carbamate 
• 22571-78-4 (+)-cis-pinononoic acid 
• 136780-45-5 methyl (1S,3R)-3-acetyl-2,2-dimethylcyclobutanecarboxylate 
• 308287-84-5 Methyl (1S,3R)-(+)-3-acetamido-2,2-dimethylcyclobutanecarboxylate 
• 188918-50-5 (1S,3R)-3-[(tert-butoxycarbonyl)amino]-2,2-dimethylcyclobutane-1-carboxylic acid 

Relevant articles and documents

NOVEL BETULINIC ACID DERIVATIVES AS HIV INHIBITORS

(I)The invention relates to novel novel betulinic acid derivatives and related compounds, and pharmaceutical compositions useful for therapeutic treatment of viral diseases and particularly HIV mediated diseases.

Chiral 1,3-cyclobutane amino acids: Syntheses and extended conformations

Optically active samples of the N-protected 1,3-cyclobutane amino acids 1 and 2 were prepared from α-pinene. The synthesis of 1 is enantiodivergent insofar as both optical antipodes of the product can be prepared from the same α-pinene enantiomer. Single crystal X-ray diffraction studies of derivatives of 1 reveal these compounds can have extended conformations.