52780-15-1

Usage

Uses

Used in Pharmaceutical Industry:
3-Bromo-2-methylbenzonitrile is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Bromo-2-methylbenzonitrile serves as an intermediate in the production of various agrochemicals, contributing to the development of effective pest control and crop protection solutions.
Used in Dye and Pigment Production:
3-Bromo-2-methylbenzonitrile is utilized as a building block in the creation of dyes and pigments, playing a crucial role in the formulation of colorants for various applications, including textiles, plastics, and printing inks.
Used in Organic Compound Synthesis:
3-Bromo-2-methylbenzonitrile is also employed in the synthesis of other organic compounds, broadening its applications across different industries that rely on organic chemistry for product development.

Upstream product

• 69321-60-4 2,6-dibromotoluene 
• 919363-09-0 3-bromo-2-methylbenzamide 
• 407-25-0 trifluoroacetic anhydride 
• 55289-36-6 3-bromo-2-methylaniline 
• 21900-48-1 3-bromo-2-methylbenzoic acid chloride 
• 76006-33-2 3-bromo-2-methylbenzoic acid 

Downstream Products

• 919363-09-0 3-bromo-2-methylbenzamide 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 52779-76-7 1-(3-bromo-2-methylphenyl)ethan-1-one 
• 1233479-42-9 1-bromo-2-(bromomethyl)-3-cyanobenzene 
• 1466528-33-5 (R,E)-N-(1-(3-bromo-2-methylphenyl)ethylidene)-2-methylpropane-2-sulfinamide 
• 1466528-34-6 (R)-N-(1-(3-bromo-2-methylphenyl)ethyl)-2-methylpropane-2-sulfonamide 
• 1213520-94-5 (R)-1-(3-bromo-2-methylphenyl)ethanamine 
• 1466528-35-7 tert-butyl (R)-(1-(3-bromo-2-methylphenyl)ethyl)carbamate 
• 1466528-32-4 (R)-tert-butyl 1-(3-(1-benzyl-1H-pyrazol-4-yl)-2-methylphenyl)ethylcarbamate 
• 35256-74-7 2-methyl-3-cyano-benzoyl chloride 
• 2239273-34-6 3-(2-amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile 
• 3843-99-0 2-methyl-3-cyano-benzoic acid 
• 52779-94-9 2-[3-(2-thenoyl)-o-tolyl] acetic acid 

Relevant academic research and scientific papers

PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS

Provided herein are improved processes for preparing aminopyrimidine compounds of Formula (I). The disclosed processes advantageously proceed through a β-diketoester intermediate of Formula (A) and avoid the direct linking of a pyrimidine and phenyl moiet

Development of a Scalable and Practical Synthesis of AB928, a Dual A2a/A2bReceptor Antagonist

AB928 is a potent and selective dual antagonist of the A2a and A2b receptors, which is currently in clinical trials. Here, we report the development of two scalable and practical syntheses of AB928. The first-generation synthesis was used to successfully

DIFLUOROMETHYLENE COMPOUND

The present invention relates to a compound having an URAT1 inhibitory activity, and to an URAT1 inhibitor, a blood uric acid level-reducing agent and a pharmaceutical composition containing the compound. More specifically, the present invention relates to a compound represented by the formula (I): wherein R1 is -Q1-A1 or the like; R2 is a hydrogen atom, a halogen atom, a lower alkyl group or the like; W1, W2, W3 and W4 are each independently a nitrogen atom or a methine group optionally having substituents, or the like; X and Y are each a single bond, an oxygen atom or the like; Z is a hydroxyl group or COOR3 or the like.

Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents

A series of boron-containing benzoxaborole compounds was designed and synthesized for a structure-activity relationship investigation surrounding 7-(HOOCCH2CH2)-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (1) with the goal of discovering

PYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF PKC-THETA

Disclosed are novel compounds of formula (I) wherein R1, R2, R3 , R4 and A are as defined herein, which are useful as inhibitors of PKC-theta and are thus useful for treating a variety of diseases and disorders

STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.

STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.

STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.

Steroid receptor modulator compounds and methods

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.

STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.