52791-88-5Relevant academic research and scientific papers
Substitutions and dehydrogenations by 2,2-bis(trifluoromethyl)-ethylene-1,1-dicarbonitrile via hydride abstraction
Brueckner, Reinhard,Huisgen, Rolf
, p. 1875 - 1878 (2007/10/02)
Substitution of benzylic H by the title compound (BTF) gives rise to products with -CH(CF3)2 terminus exclusively; an intermediate benzylic ion pair results from hydride transfer. Instead of ion recombination, proton transfer may be the concluding step generating dehydrogenation products and 2,2-bis(trifluoromethyl)ethane-1,1-dicarbonitrile.
Transformation of α-assisted carbanions into the corresponding trimethylsiloxy derivatives using bis(trimethylsilyl)peroxide
Dembech,Guerrini,Ricci,Seconi,Taddei
, p. 2999 - 3006 (2007/10/02)
The reaction of bis(trimethylsilyl)peroxide with tlithium derivatives of sulphides and nitriles is reported to give the corresponding O-trimethylsilyl hemithioacetals and cyanohydrins. From these products the carbonyl function can be exposed in acidic media or in the presence of fluoride ions. This methodology provides an attractive route to transform a CH2-X group (X = PhS, MeS or CN) into the corresponding CHO, allowing the preparation of aldehydes that can be considered difficult to prepare such as, for example, formyltrimethylsilane which was generated and trapped in situ using a Wittig reaction.
Metalation reactions. VIII. Metalation of benzyl methyl sulfide
Cabiddu, Salvatore,Floris, Constantino,Melis, Stefana,Sotgiu, Francesca
, p. 61 - 64 (2007/10/02)
The metalation of benzylmethyl sulfide with n-butyllithium in hexane and in the presence of TMEDA has been investigated.The results show that metalation occurs only at the benzylic position with no wittig type rearrangement, cleavage of thioether bond and
