52806-37-8

Basic information

• Product Name: (4,5-dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl)methanone
• Synonyms: (4,5-dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl)methanone
• CAS NO: 52806-37-8
• Molecular Weight: 316.354
• Mol File: 52806-37-8.mol

Chemical Properties

• CAS DataBase Reference: (4,5-dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl)methanone(52806-37-8)
• EPA Substance Registry System: (4,5-dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl)methanone(52806-37-8)

Safety Data

• Hazardous Substances Data: 52806-37-8(Hazardous Substances Data)

Upstream product

• 494-99-5 1,2-dimethoxy-4-methylbenzene 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 93-07-2 Veratric acid 
• 7721-62-2 4,5-dimethoxy-2-methylbenzaldehyde 
• 102415-87-2 (4,5-dimethoxy-2-methylphenyl)-(3,4-dimethoxyphenyl)-methane 
• 64-19-7 acetic acid 
• 7446-08-4 selenium(IV) oxide 

Downstream Products

• 1582229-77-3 N-((4,5-dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl)methyl)methanesulfonamide 
• 1582229-74-0 (4,5-dimethoxy-2-methylphenyl)(3,4-dimethoxyphenyl)methanamine hydrochloride 
• 1582229-71-7 1-[azido(3,4-dimethoxyphenyl)methyl]-4,5-dimethoxy-2-methylbenzene 
• 154502-82-6 1-(3,4-dimethoxyphenyl)-1,4-dihydro-6,7-dimethoxy-3H-2-benzopyran-3-one 
• 154502-77-9 2-<2-(3,4-dimethoxybenzoyl)-4,5-dimethoxyphenyl>acetic acid 
• 101788-16-3 4,5,3',4'-Tetramethoxy-2-methyl-benzhydrol 

Relevant articles and documents

Synthesis and biological evaluation of novel bromophenol derivatives as carbonic anhydrase inhibitors

Here, we provide an alternative synthesis of the natural bromophenol 3,4-dibromo-5-(2,3-dibromo-4,5- dihydroxybenzyl)-6-(ethoxymethyl)benzene-1,2- diol (3) and the first synthesis of (4,5-dihydroxy-2- methylphenyl)(3,4- dihydroxyphenyl)methanone (18) and

Synthesis and carbonic anhydrase isoenzymes i and II inhibitory effects of novel benzylamine derivatives

Synthesis and carbonic anhydrase inhibitory properties of novel diarylmethylamines 22-25 and sulfonamide derivatives 26-28 were investigated. Acylation of methoxy-substituted benzenes with benzene carboxylic acids, reduction of ketones with NaBH4, conversion of alcohols to azides, Pd-C catalyzed hydrogenation of azides afforded title compounds 22-25. Compounds 22, 24 and 25 were converted to sulfonamide derivatives 26-28 with MeSO2Cl. The inhibitory effects of novel benzylamine derivatives 22-28 were tested on human carbonic anhydrase (hCA, EC 4.2.1.1) isozymes hCA I and II. The results demonstrated that compound 28 was found to be the best inhibitor against both hCA I (Ki: 3.68 μM) and hCA II (Ki: 9.23 μM).