52829-97-7

Upstream product

• 765-43-5 Cyclopropyl methyl ketone 
• 149-73-5 trimethyl orthoformate 
• 67-56-1 methanol 
• 66031-87-6 (1-methoxyethenyl)cyclopropane 
• 124-41-4 sodium methylate 
• 96246-32-1 1-chloro-1-cyclopropyl-1-nitroethane 
• 6746-94-7 Cyclopropylacetylene 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 1187885-13-7 (1-cyclopropylvinylsulfanyl)-benzene 
• 6746-94-7 Cyclopropylacetylene 

Relevant academic research and scientific papers

Preparation method for compound containing alkynyl and cyclopropyl

The invention relates to the field of organic synthesis, and discloses a preparation method for a compound containing alkynyl and cyclopropyl. The method comprises the following steps: a compound ii with alkyne and alkene is taken as a starting raw material, under effects of a catalyst, the compound ii with the alkyne and the alkene and a diazo substance iv are mixed and reacted in a solvent, andtherefore a reaction liquid containing a compound iii is obtained; and the obtained reaction liquid is added into acid water or hot water for washing, then an inorganic alkali or an organic alkali isadded to adjust the pH to 8-14, and therefore the compound I containing the alkynyl and the cyclopropyl is obtained. The method provided by the invention has the following beneficial effects: 1) the yield of the reaction is improved; 2) the industrialized raw materials used by the method are cheap and easy to obtain; and 3) by-products are reduced, and environmental pollution is reduced.

A fluorinated cobalt(III) porphyrin complex for hydroalkoxylation of alkynes

A fluorinated cobalt(III) porphyrin complex [Co(TPFPP)-NTf2·2C2H5OH, where TPFPP=5,10,15,20-tetrakis(penta-fluorophenyl)porphyrin, Tf=CF3SO2] promotes hydroalkoxylation of alkynes to give acetals in good to excellent yields. The acetals can be directly functionalized with nucleophiles in a one-pot procedure.

PROCESS FOR THE SYNTHESIS OF ETHYNYLCYCLOPROPANE

Ethynylcyclopropane is prepared in a two-step process by reacting (1,1-dimethoxyethyl)- cyclopropane with a thiol and eliminating the thiol from the intermediate.

Process for the preparation of ethynylcyclopropane

Ethynylcyclopropane is prepared from (1,1-dimethoxyethyl)cyclopropane by a two-stage elimination of methanol. Ethynylcyclopropane is an intermediate in the synthesis of pharmaceutically active ingredients, for example, antiviral agents.

Influence of Solvent and Counterion in the Reactions of Alkoxide Ions with the 2-Nitropropan-2-yl Radical

Photostimulated free radical chain reactions between alkoxide ions derived from primary alcohols and XCMe2NO2 (X= Cl, Br, NO2, PhSO2, N3, or p-ClC6H4S) occur to produce Me2C(OR)2 by reaction involving the trapping of Me2C(NO2). by RO-, the decomposition of ROCMe2NO2.- to ROCMe2., and the oxidation of ROCMe2. to Me2C=OR+ by XCMe2NO2.