52834-08-9

Basic information

• Product Name: 4-AMINO-5-BROMO NICOTINIC ACID
• Synonyms: 4-AMINO-5-BROMO NICOTINIC ACID;3-Pyridinecarboxylic acid, 4-aMino-5-broMo-;4-amino-5-bromo-3-Pyridinecarboxylic acid;4-amino-5-bromopyridine-3-carboxylic acid
• CAS NO: 52834-08-9
• Molecular Formula: C6H5BrN2O2
• Molecular Weight: 217.0201
• Product Categories: Pyridine
• Mol File: 52834-08-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 396.6 °C at 760 mmHg
• Flash Point: 193.7 °C
• Appearance: /
• Density: 1.909 g/cm³
• Vapor Pressure: 5.3E-07mmHg at 25°C
• Refractive Index: 1.685
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-AMINO-5-BROMO NICOTINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-5-BROMO NICOTINIC ACID(52834-08-9)
• EPA Substance Registry System: 4-AMINO-5-BROMO NICOTINIC ACID(52834-08-9)

Safety Data

• Hazardous Substances Data: 52834-08-9(Hazardous Substances Data)

Usage

General Description

4-Amino-5-Bromo Nicotinic Acid is a chemical compound with the molecular formula C6H6BrNO2. 4-AMINO-5-BROMO NICOTINIC ACID belongs to the family of Pyridines and derivatives, specifically a Nicotinic acid. It is used in the chemistry and pharmaceutical industries due to its diverse set of properties. The presence of a bromine atom makes it a useful intermediate in a variety of chemical reactions typically utilized in the synthesis of more complex compounds. Notably, it has a role to play in the formulation of pharmaceutical products. It should be handled with caution due to its potentially reactive nature. Likely areas of research involving this compound include drug synthesis and the development of new chemical processes.

InChI:InChI=1/C6H5BrN2O2/c7-4-2-9-1-3(5(4)8)6(10)11/h1-2H,(H2,8,9)(H,10,11)

Upstream product

• 41276-30-6 C₉H₁₄O₃NC₆H₅ 
• 67848-59-3 4-piperidone-3-carboxylic acid ethyl ester 
• 7418-65-7 4-aminonicotinic acid 

Relevant articles and documents

Preparation method of nicotinic acid derivative

The invention relates to a preparation method of a nicotinic acid derivative. The method comprises the following steps: with N-benzylpiperidine-4-keto-3-formate as a raw material, carrying out a hydrogenolysis reaction to obtain piperidine-4-keto-3-formate; performing halogenation reaction with a certain amount of a halogenation reagent to obtain 3,5-dihalogenated piperidine-4-one-3-formate or 3,5,5-trihalogenated piperidine-4-one-3-formateperforming one-pot process with different alkaline reagent for removing halogen hydride through elimination, and performing hydrolysis and performing acidification with hydrochloric to generate corresponding nicotinic acid derivatives: 4-hydroxynicotinic acid, 4-aminonicotinic acid, 4-hydroxy-5-chloronicotinic acid, 4-amino-5-chloronicotinic acid and 4-amino-5-bromonicotinic acid. The method is simple and convenient to operate, mild in condition, short in technological process, low in wastewater amount, environmentally friendly and low in cost, and green industrial production of the nicotinic acid derivative is facilitated.

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