52834-08-9

Usage

Uses

Used in Chemical Synthesis:
4-Amino-5-Bromo Nicotinic Acid is used as a chemical intermediate for the synthesis of more complex compounds. Its unique structure and reactivity make it a valuable component in the development of new chemical processes.
Used in Pharmaceutical Industry:
4-Amino-5-Bromo Nicotinic Acid is used as a key ingredient in the formulation of pharmaceutical products. Its presence in these products is attributed to its potential role in drug synthesis, contributing to the development of novel therapeutic agents.
Used in Drug Research and Development:
4-Amino-5-Bromo Nicotinic Acid is used as a research compound in the field of drug synthesis and the development of new chemical processes. Its potential applications in this area make it a subject of interest for scientists and researchers working on innovative pharmaceutical solutions.
It is important to handle 4-Amino-5-Bromo Nicotinic Acid with caution due to its potentially reactive nature, ensuring safety in both laboratory and industrial settings.

InChI:InChI=1/C6H5BrN2O2/c7-4-2-9-1-3(5(4)8)6(10)11/h1-2H,(H2,8,9)(H,10,11)

Upstream product

• 7418-65-7 4-aminonicotinic acid 
• 67848-59-3 4-piperidone-3-carboxylic acid ethyl ester 
• 41276-30-6 C₉H₁₄O₃NC₆H₅ 

Relevant academic research and scientific papers

Preparation method of nicotinic acid derivative

The invention relates to a preparation method of a nicotinic acid derivative. The method comprises the following steps: with N-benzylpiperidine-4-keto-3-formate as a raw material, carrying out a hydrogenolysis reaction to obtain piperidine-4-keto-3-formate; performing halogenation reaction with a certain amount of a halogenation reagent to obtain 3,5-dihalogenated piperidine-4-one-3-formate or 3,5,5-trihalogenated piperidine-4-one-3-formateperforming one-pot process with different alkaline reagent for removing halogen hydride through elimination, and performing hydrolysis and performing acidification with hydrochloric to generate corresponding nicotinic acid derivatives: 4-hydroxynicotinic acid, 4-aminonicotinic acid, 4-hydroxy-5-chloronicotinic acid, 4-amino-5-chloronicotinic acid and 4-amino-5-bromonicotinic acid. The method is simple and convenient to operate, mild in condition, short in technological process, low in wastewater amount, environmentally friendly and low in cost, and green industrial production of the nicotinic acid derivative is facilitated.

Pyrido-pyrimidines, its preparation and use

The invention discloses pyridopyrimidine compounds with a general formula (I), wherein Ar is aryl or heteroaryl; R1 is hydrogen, halogen, amino, heterocyclic group, alkyl, aminoalkyl, heterocyclic alkyl, aryl, heteroaryl, cyano, alkenyl or alkynyl; R2 is

TRICYCLIC GUANIDINE DERIVATIVE

Disclosed are compounds useful as inhibitors of Phosphodiesterase 1 (PDE1), compositions thereof, and methods of using the same.

FUSED PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF HIV

Described herein are compounds of Formula (I) and tautomers and pharmaceutical salts thereof, compositions and formulations containing such compounds, and methods of using and making such compounds.

Inhibiting the growth of weeds with 2-substituted pyrdidopyimidines and salts thereof

2-Substituted pyridopyrimidines and their alkali and alkylamine salts as herbicides, and processes for the synthesis of starting materials leading to the preparation thereof.