5284-78-6Relevant articles and documents
Synthesis and characterization of a novel class of protein tyrosine phosphatase inhibitors
Ibrahimi, Omar A.,Wu, Li,Zhao, Kang,Zhang, Zhong-Yin
, p. 457 - 460 (2000)
Nonpeptidyl aryloxymethylphosphonates were prepared and evaluated as protein tyrosine phosphatase inhibitors. The results suggest that aryloxymethylphosphonates are effective nonhydrolyzable phosphotyrosine surrogates and provide further insight into the molecular mechanisms by which phosphate mimics inhibit phosphatase function. (C) 2000 Elsevier Science Ltd. All rights reserved.