52856-25-4

Upstream product

• 173280-47-2 (4-Chloro-phenyl)-bis-(2,6-dimethoxy-phenyl)-methanol 
• 13190-50-6 4-dimethylaminophenyllithium 
• 14774-78-8 4-chlorophenyl lithium 
• 16932-48-2 2,2',6,6'-tetramethoxybenzophenone 
• 94-30-4 ethyl 4-methoxybenzoate 
• 173280-48-3 Bis-(2,6-dimethoxy-phenyl)-(4-dimethylamino-phenyl)-methanol 
• 173280-46-1 Bis-(2,6-dimethoxy-phenyl)-(4-methoxy-phenyl)-methanol 

Downstream Products

• 193153-83-2 1-(2,6-dimethoxyphenyl)-4-[bis(2,6-dimethoxyphenyl)methylene]-2,5-cyclohexadien-1-ol 

Relevant academic research and scientific papers

Facile Aromatic Nucleophilic Substitutioins Observed for the Triarylcarbenium Ions, +

Triarylmethanols of type (4-YC6H4)Φ2COH were prepared.The methanol, (4-MeOC6H4)Φ2COH, reacted with acids in a variety of solvents to give the triarylcarbenium salts, X or X, or 4-bis(2,6-dimethoxyphenyl)methylene-2,5-cyclohexadienone, O=C6H4=CΦ2, depending on the conditions.These carbenium salts further reacted in alcohols, ROH, to give the triarylmethanes, (4-ROC6H4)Φ2CH (R=Me, Et), where the para-substituent, MeO or HO, was substituted by the solvent, accompanied by a reduction at the central c arbon.The methanol, (4-ClC6H4)Φ2COH, also reacted with acid to give the carbenium salt or the triarylmethane, depending on the conditions.While the methanol, (4-Me2NC6H4)Φ2COH, also gave the carbenium salt, -X, it was inert against the formation of the triarylmethane under analogous conditions.It reacted with aqueous sodium hydroxide to give O=C6H4=CΦ2 rather than the original methanol.The para-substituent of X was substituted by di- and monoalkylamines, RR'NH, to give X (R,R'=Me,Me; Et,Et; Me,H; Et,H; Bu,H).While X reacted with the dialkylamines to give X, it reacted with monoalkylamines, RNH2, to give X. X was hydrolyzed in the presence of diethylamine to give O=C6H4=CΦ2, but reacted with monoalkylamines to give RN=C6H4=CΦ2.