528567-33-1

Basic information

• Product Name: (2R)-5-Methoxy-1,3-oxathiolane-2-Methanol 2-Benzoate
• Synonyms: (2R)-5-Methoxy-1,3-oxathiolane-2-Methanol 2-Benzoate
• CAS NO: 528567-33-1
• Molecular Formula: C₁₂H₁₄O₄S
• Molecular Weight: 254.30216
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 528567-33-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform
• CAS DataBase Reference: (2R)-5-Methoxy-1,3-oxathiolane-2-Methanol 2-Benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-5-Methoxy-1,3-oxathiolane-2-Methanol 2-Benzoate(528567-33-1)
• EPA Substance Registry System: (2R)-5-Methoxy-1,3-oxathiolane-2-Methanol 2-Benzoate(528567-33-1)

Safety Data

• Hazardous Substances Data: 528567-33-1(Hazardous Substances Data)

Usage

Chemical Properties

Colorless Oil

Upstream product

• 98-88-4 benzoyl chloride 
• 146922-46-5 5-methoxy-2-hydroxymethyl[1,3]oxathiolane 
• 528567-31-9 menthyl 5-hydroxy[1,3]oxathiolane-2-carboxylate 

Downstream Products

• 1091585-30-6 ((2R,5S)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl benzoate 
• 528567-35-3 methyl 1-(2-benzoyloxymethyl-α-L-[1,3]oxatholan-5-yl)imidazole-4-carboxylate 

Relevant articles and documents

A PROCESS FOR STEREOSELECTIVE SYNTHESIS OF LAMIVUDINE

The present invention discloses a process for stereoselective synthesis of Lamivudine comprising the following steps: (a) performing a glycosylation reaction between the compound of formula (I) and cytosine or protected cytosine, and separating the reaction product by recrystallization to obtain the intermediate of formula (II); and (b) deprotecting the intermediate of formula (II) to obtain Lamivudine.