528588-35-4Relevant academic research and scientific papers
Efficient and stereoselective synthesis of novel cis-4-substituted proline analogues
Zhang, Junyi,Wang, Wei,Xiong, Chiyi,Hruby, Victor J.
, p. 1413 - 1415 (2003)
A series of novel cis-4-substituted proline analogues were designed and synthesized. Highly stereoselective alkylations at the γ-position of glutamic ester 2 were achieved, followed by reduction, mesylation, and cyclization to afford the title compounds 1 in good yields and high diastereoselectivity.
