52864-95-6Relevant academic research and scientific papers
Naphthyl and tetrahydronaphthyl di-ethers
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, (2008/06/13)
Naphthyl and tetrahydronaphthyl diethers of the formula STR1 wherein A represents a naphthylene group or a 5,6,7,8-tetrahydronaphthylene group having their ether chains attached to the 1 and 2 or 2 and 3 positions or, when A represents a naphthylene group, to the 1 and 8 positions, which aromatic groups may also have substituted therein one to three substituents selected from halogen atoms, lower alkyl, lower alkenyl, benzyl, nitro and lower acyl groups, said substituents being present in the aromatic part in case A represents a 5,6,7,8-tetrahydronaphthylene group and R represents an isopropyl or tertiary butyl group, and acid addition salts thereof. The compounds are useful anti-arrhythmic agents and also show local anaesthetic activity in mammals.
