52875-47-5

Usage

Uses

Used in Organic Synthesis:
7,10-Dioxadispiro[2.2.4.2]dodecane is used as a building block in organic synthesis for its interesting and complex molecular structure, which allows for the creation of novel materials and compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 7,10-Dioxadispiro[2.2.4.2]dodecane is utilized as a building block for the development of new pharmaceuticals, thanks to its unique structure that can contribute to the design of innovative drugs.
Used in Agrochemical Development:
7,10-Dioxadispiro[2.2.4.2]dodecane is employed as a component in the development of agrochemicals, where its complex structure can be leveraged to create new products for agricultural applications.
Used in Drug Delivery Systems:
7,10-Dioxadispiro[2.2.4.2]dodecane has been studied for its potential use in drug delivery systems, where its unique structure could enhance the delivery and effectiveness of pharmaceutical agents.
Used as a Chiral Building Block:
7,10-Dioxadispiro[2.2.4.2]dodecane is used as a chiral building block in the synthesis of complex molecules, which is valuable in creating enantiomerically pure compounds for various applications, including pharmaceuticals and agrochemicals.

Upstream product

• 910635-75-5 rac-1-(3-ethyl-5-methyl-4,5,6,7-tetrahydrobenzo[c]thiophen-1-yl)ethanone 
• 75-11-6 diiodomethane 
• 51656-90-7 8-methylene-1,4-dioxaspiro[4.5]decane 
• 624-73-7 1,2-Diiodoethane 
• 186581-53-3 diazomethane 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Downstream Products

• 1424996-19-9 C₂₉H₃₂N₂O₅S 
• 1424995-28-7 C₁₅H₁₆N₂O₃ 
• 1424995-31-2 C₂₄H₂₃NO₄ 
• 1424995-32-3 C₂₅H₂₅NO₄ 
• 910636-73-6 C₂₃H₂₆O₂S 
• 1516885-76-9 (S)-N-(3-(2-ethyl-4-(5-(3-ethyl-6,7-dihydro-4H-spiro[benzo[c]thiophene-5,1'-cyclopropan]-1-yl)-1,2,4-oxadiazol-3-yl)-6-methylphenoxy)-2-hydroxypropyl)-2-hydroxyacetamide 
• 99799-73-2 spiro[2.5]octane-6-amine 
• 15811-21-9 spiro[2.5]octan-6-one 

Relevant academic research and scientific papers

KINASE INHIBITORS

Disclosed herein are protein kinase inhibitors, in particular Bruton's tyrosine kinase (BTK) inhibitors, pharmaceutical compositions comprising them, processes for preparing them and uses of such protein kinase inhibitors to treat or prevent diseases, disorders and conditions associated with kinase function. In particular, the present invention relates to selective BTK inhibitors.

N-(PYRIDIN-2-YLSULFONYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF A CFTR MEDIATED DISEASE

The invention relates to heterocyclic compounds of the formula (I), in which all of the variables are as defined in the specification; capable of modulating the activity of CFTR. The invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including Cystic fibrosis and related disorders.

PYRROLO[2,3-C]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE

Disclosed are a pyrrolo[2,3-c]pyridine derivative, a preparation method therefor, and use thereof in medicine. Specifically, disclosed are a pyrrolo[2,3-c]pyridine derivative as represented by general formula (1), a preparation method therefor, a pharmaceutical composition comprising the derivative, as well as use thereof as a BRD4 inhibitor in the treatment of related diseases such as cancers, inflammations, chronic liver diseases, diabetes, cardiovascular diseases and AIDS, each substituent in general formula (I) being same as defined in the description.

Novel S1P1 receptor agonists - Part 2: From bicyclo[3.1.0] hexane-fused thiophenes to isobutyl substituted thiophenes

Previously, we reported on the discovery of a novel series of bicyclo[3.1.0]hexane fused thiophene derivatives that serve as potent and selective S1P1 receptor agonists. Here, we discuss our efforts to simplify the bicyclohexane fused thiophene

CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

HEPATITIS C INHIBITOR COMPOUNDS

A compound of formula (I) useful for the treatment or prevention of hepatitis C viral infection, (Formula (I)) wherein: X1 and X2 are each independently CRB or N; RB is H, (C1-6)alkyl, (C1-6/sub

Hydrogenated Benzo (C) Thiophene Derivatives as Immunomodulators

The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.

HYDROGENATED BENZO (C) THIOPHENE DERIVATIVES AS IMMUNOMODULATORS

The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.