52888-72-9

Usage

Uses

Used in Food Industry:
Benzoic acid, 5-(1,1-dimethylethyl)-2-hydroxy-, methyl ester is used as a food preservative for its ability to prevent spoilage of food products by inhibiting the growth of mold, yeast, and bacteria. It is particularly effective in acidic environments.
Used in Fragrance Industry:
This chemical is also used as a fragrance ingredient, adding pleasant scents to various products.
Used in Personal Care Products:
Benzoic acid, 5-(1,1-dimethylethyl)-2-hydroxy-, methyl ester is utilized in the manufacturing of personal care products, such as cosmetics and skincare items, due to its preservative and antioxidant properties.
Used in Pharmaceutical Industry:
In addition to its use in food and personal care products, this chemical is also employed in the production of pharmaceuticals, where its preservative and antioxidant properties are beneficial in maintaining the quality and stability of medications.

Upstream product

• 56-23-5 tetrachloromethane 
• 87-19-4 isobutyl salicylate 
• 7637-07-2 boron trifluoride 
• 75-65-0 tert-butyl alcohol 
• 119-36-8 methyl salicylate 
• 534-22-5 2-methylfuran 
• 20607-85-6 methyl 4,4-dimethyl-2-pentynoate 
• 507-19-7 t-butyl bromide 
• 98-54-4 para-tert-butylphenol 
• 67-56-1 methanol 
• 16094-31-8 5-tert-butylsalicylic acid 

Downstream Products

• 16094-31-8 5-tert-butylsalicylic acid 
• 59238-52-7 5-tert-Butyl-2-(N-phenyl-benzimidoyloxy)-benzoic acid methyl ester 
• 59238-70-9 5-tert-Butyl-2-[N-(4-tert-butyl-phenyl)-benzimidoyloxy]-benzoic acid methyl ester 
• 867218-25-5 5-tert-butyl-2-{3,5-difluoro-4-(1-methyl-3-phenyl-propylamino)-6-[3-(5-trifluoromethyl-[1,2,4]oxadiazol-3-yl)-phenoxy]-pyridin-2-yloxy}-benzoic acid methyl ester 
• 59238-73-2 2-[Benzoyl-(4-tert-butyl-phenyl)-amino]-5-tert-butyl-benzoic acid methyl ester 
• 59238-35-6 2-Carboxy-4,4'-di-t-butyldiphenylamin 
• 59238-50-5 5-tert-Butyl-2-[N-(2-tert-butyl-phenyl)-benzimidoyloxy]-benzoic acid methyl ester 

Relevant academic research and scientific papers

WDR5-MYC INHIBITORS

Substituted N-phenyl sulfonamide compounds inhibit WDR5-MYC interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.

Synthesis method of 5-tert-butyl-2-methyl hydroxybenzoate

The invention discloses a synthesis method of methyl 5-tert-butyl-2-hydroxybenzoate, and belongs to the technical field of organic synthesis. The synthesis method comprises the following steps of: S1,taking methyl salicylate and tert-butyl alcohol as raw materials, and preparing a mixture of a compound shown as a formula (I), a compound shown as a formula (II) and a compound shown as a formula (III) under the catalytic action of concentrated sulfuric acid; and S2, carrying out a rearrangement reaction on the mixture prepared in the step S1 under the catalysis of Lewis acid, and carrying out post-treatment to prepare a pure compound shown in the formula (I), namely the 5-tert-butyl-2-methyl hydroxybenzoate. The synthesis method of the 5-tert-butyl-2-methyl hydroxybenzoate is low in production cost, novel in preparation route, simple in equipment and easy for industrial production, and can be widely applied to the field of production of fine chemicals.

METHOD TO PREPARE PHENOLICS FROM BIOMASS

The present invention is directed to a method for preparing a final phenolic product from biomass comprising the steps of providing a furanic compound obtainable from biomass; reacting the furanic compound with a dienophile to obtain a phenolic compound; reacting the phenolic compound further to obtain the final phenolic product.

COMPOUNDS USEFUL FOR THE TREATMENT OF METABOLIC DISORDERS AND SYNTHESIS OF THE SAME

The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex

The activated Factor VII/tissue factor complex (FVIIa/TF) plays a key role in the formation of blood clots. Inhibition of this complex may lead to new antithrombotic drugs. An X-ray crystal structure of a fluoropyridine-based FVIIa/TF inhibitor bound in the active site of the enzyme complex suggested that incorporation of substitution at the 5-position of the hydroxybenzoic acid side chain could lead to the formation of more potent inhibitors through interactions with the S1′/S2′ pocket.

OPIOID RECEPTOR ACTIVE COMPOUNDS

The invention provides compounds of formula I: wherein R1 to R4 and n have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating pain and treating other conditions which involve, for example, binding opioid receptors using compounds of formula I.