52938-99-5

Usage

Uses

Used in Pharmaceutical Industry:
5-(4-Methoxyphenyl)-2-furoic acid is used as a building block for the development of new drugs due to its unique chemical properties and potential biological activities. Its structural characteristics allow it to be a valuable component in the synthesis of pharmaceutical compounds with therapeutic applications.
Used in Organic Synthesis:
5-(4-Methoxyphenyl)-2-furoic acid is used as a key intermediate in the synthesis of various organic compounds. Its reactive functional groups and unique structure make it suitable for use in the preparation of a wide range of organic materials, including pharmaceuticals, agrochemicals, and other specialty chemicals.

InChI:InChI=1/C12H10O4/c1-15-9-4-2-8(3-5-9)10-6-7-11(16-10)12(13)14/h2-7H,1H3,(H,13,14)

Upstream product

• 88-14-2 2-furanoic acid 
• 4346-59-2 para-methoxyphenyldiazonium chloride 
• 34070-33-2 5-(4-methoxyphenyl)furan-2-carbaldehyde 
• 585-70-6 5-bromo-furan-2-carboxylic acid 
• 5720-07-0 4-methoxyphenylboronic acid 
• 104-94-9 4-methoxy-aniline 
• 52939-05-6 5-((4-methoxy)phenyl)furan-2-carboxylic acid methyl ester 
• 2527-99-3 methyl 5-bromo-2-furoate 

Downstream Products

• 908856-07-5 (R)-2-{[5-(4-Methoxy-phenyl)-furan-2-carbonyl]-amino}-3-((2E,6E)-3,7,11-trimethyl-dodeca-2,6,10-trienylsulfanyl)-propionic acid methyl ester 
• 92973-02-9 {[1-Chloro-1-[5-(4-methoxy-phenyl)-furan-2-yl]-meth-(Z)-ylidene]-amino}-acetic acid ethyl ester 
• 92972-91-3 {[5-(4-Methoxy-phenyl)-furan-2-carbonyl]-amino}-acetic acid ethyl ester 
• 93770-57-1 {5-[5-(4-Methoxy-phenyl)-furan-2-yl]-tetrazol-1-yl}-acetic acid 
• 92972-78-6 {5-[5-(4-Methoxy-phenyl)-furan-2-yl]-tetrazol-1-yl}-acetic acid ethyl ester 
• 884874-93-5 5-(4-methoxy-phenyl)-furan-2-carboxylic acid N-(3-hydroxy-benzyl)amide 
• 1144110-90-6 C₂₂H₁₈N₄O₂S₂ 
• 1211829-20-7 5-(4-trifluoromethylphenyl)-2-(4-tolyl)furan 
• 1254943-80-0 C₁₉H₁₆N₂O₅ 

Relevant academic research and scientific papers

Synthesis of 2,5-Diaryl Nonsymmetric Furans C6-Platform Chemicals via Catalytic Conversion of Biomass and the Formal Synthesis of Dantrolene

Biomass-derived commodity chemical 5-hydroxymethyl furfural is an underutilized C6-platform chemical derived from cellulose that is ideal to prepare next-generation value-added products. We have developed an efficient synthetic strategy to access 2,5-diar

Furoylamino beta-carboline compound as well as preparation method and application thereof

The invention discloses a furoylamino beta-carboline compound as well as a preparation method and application thereof. The structural general formula of the compound is shown as a formula I in the specification. The invention discloses a preparation metho

Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors

Gut microbial β-glucuronidases have drawn much attention due to their role as a potential therapeutic target to alleviate some drugs or their metabolites-induced gastrointestinal toxicity. In this study, fifteen 5-phenyl-2-furan derivatives containing 1,3

2-furoylamide compound and preparation and application thereof

The invention discloses a 2-furancarboxamide compound and a preparation method and application thereof. The 2-furancarboxamide compound is obtained by reacting a compound as shown in a formula II with9H-pyridino[3,4-b]indole in the presence of an acid-bin

Thiazolidin-2-cyanamides derivatives as novel potent Escherichia coli β-glucuronidase inhibitors and their structure–inhibitory activity relationships

Gut microbial β-glucuronidases have the ability to deconjugate glucuronides of some drugs, thus have been considered as an important drug target to alleviate the drug metabolites-induced gastrointestinal toxicity. In this study, thiazolidin-2-cyanamide de

Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors

In this present study, a series of 5-phenyl-2-furan and 4-phenyl-2-oxazole derivatives were designed and synthesized as phosphodiesterase type 4 (PDE4) inhibitors. In vitro results showed that the synthesized compounds exhibited considerable inhibitory ac

Synthesis and SAR of 5-aryl-furan-2-carboxamide derivatives as potent urotensin-II receptor antagonists

The synthesis and biological evaluation as potential urotensin-II receptor antagonists of a series of 5-arylfuran-2-carboxamide derivatives 1, bearing a 4-(3-chloro-4-(piperidin-4-yloxy)benzyl)piperazin-1-yl group, are described. The results of a systemat

Novel S-Thiazol-2-yl-furan-2-carbothioate Derivatives as Potential T3SS Inhibitors against Xanthomonas oryzae on Rice

Bacterial leaf blight (BLB) caused by Xanthomonas oryzae pv oryzae (Xoo) is considered as the most destructive disease of rice. The use of bactericides is among the most widely used traditional methods to control this destructive disease. The excessive an

Synthesis of carbohydrazides and carboxamides as anti-tubercular agents

A novel series of furan/thiophene carbohydrazides and carboxamides were synthesized and evaluated for anti-TB and cytotoxic activities. All the synthesized compounds were characterized using 1H and 13C NMR and mass spectral technique

Synthesis and biological evaluation of 2,5-disubstituted furan derivatives as P-glycoprotein inhibitors for Doxorubicin resistance in MCF-7/ADR cell

Multidrug resistance (MDR) is a tendency in which cells become resistant to structurally and mechanistically unrelated drugs, which is mediated by P-glycoprotein (P-gp). It is one of the noteworthy problems in cancer therapy. As one of the most important