52938-99-5

Basic information

• Product Name: 5-(4-Methoxyphenyl)-2-furoic acid
• Synonyms: 5-(2-METHOXYPHENYL)-4-FUROIC ACID;5-(4-METHOXYPHENYL)-2-FUROIC ACID;5-(4-METHOXY-PHENYL)-FURAN-2-CARBOXYLIC ACID;AKOS BAR-0048;AKOS B025034;ART-CHEM-BB B025034;CHEMBRDG-BB 4401950;5-(4-Methoxyphenyl)-furane-2-carboxylic acid
• CAS NO: 52938-99-5
• Molecular Formula: C₁₂H₁₀O₄
• Molecular Weight: 218.21
• Product Categories: Building Blocks;Furans;Heterocyclic Building Blocks;Building Blocks;C12 to C20+;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 52938-99-5.mol
• Article Data: 24

Chemical Properties

• Melting Point: 182-186 °C (dec.)(lit.)
• Boiling Point: 401.5 °C at 760 mmHg
• Flash Point: 196.6 °C
• Appearance: /
• Density: 1.253g/cm³
• Vapor Pressure: 3.64E-07mmHg at 25°C
• Refractive Index: 1.565
• PKA: 3.28±0.10(Predicted)
• CAS DataBase Reference: 5-(4-Methoxyphenyl)-2-furoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-Methoxyphenyl)-2-furoic acid(52938-99-5)
• EPA Substance Registry System: 5-(4-Methoxyphenyl)-2-furoic acid(52938-99-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 52938-99-5(Hazardous Substances Data)

Usage

General Description

5-(4-Methoxyphenyl)-2-furoic acid is a chemical compound with the molecular formula C11H10O4. It is a derivative of furoic acid, which is a heterocyclic compound containing a furan ring. The presence of a 4-methoxyphenyl group on the furoic acid molecule gives it unique chemical properties. 5-(4-Methoxyphenyl)-2-furoic acid has potential applications in the field of pharmaceuticals and organic synthesis due to its structural and chemical characteristics. It has been studied for its potential biological activities and could be a valuable building block in the development of new drugs and materials.

InChI:InChI=1/C12H10O4/c1-15-9-4-2-8(3-5-9)10-6-7-11(16-10)12(13)14/h2-7H,1H3,(H,13,14)

Upstream product

• 34070-33-2 5-(4-methoxyphenyl)furan-2-carbaldehyde 
• 585-70-6 5-bromo-furan-2-carboxylic acid 
• 5720-07-0 4-methoxyphenylboronic acid 
• 88-14-2 2-furanoic acid 
• 104-94-9 4-methoxy-aniline 
• 52939-05-6 5-((4-methoxy)phenyl)furan-2-carboxylic acid methyl ester 
• 4346-59-2 para-methoxyphenyldiazonium chloride 
• 2527-99-3 methyl 5-bromo-2-furoate 

Downstream Products

• 1144110-90-6 C₂₂H₁₈N₄O₂S₂ 
• 1211829-20-7 5-(4-trifluoromethylphenyl)-2-(4-tolyl)furan 
• 126739-60-4 2-(4′-methoxyphenyl)-5-(4′-nitrophenyl)furan 
• 1620069-06-8 (S)-N-(3-(1-(2-((2-hydroxypropyl)amino)pyrimidin-4-yl)-1H-imidazole-2-carbonyl)phenyl)-5-(4-methoxyphenyl)furan-2-carboxamide 

Relevant articles and documents

Synthesis of 2,5-Diaryl Nonsymmetric Furans C6-Platform Chemicals via Catalytic Conversion of Biomass and the Formal Synthesis of Dantrolene

Biomass-derived commodity chemical 5-hydroxymethyl furfural is an underutilized C6-platform chemical derived from cellulose that is ideal to prepare next-generation value-added products. We have developed an efficient synthetic strategy to access 2,5-diar

Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors

Gut microbial β-glucuronidases have drawn much attention due to their role as a potential therapeutic target to alleviate some drugs or their metabolites-induced gastrointestinal toxicity. In this study, fifteen 5-phenyl-2-furan derivatives containing 1,3

Thiazolidin-2-cyanamides derivatives as novel potent Escherichia coli β-glucuronidase inhibitors and their structure–inhibitory activity relationships

Gut microbial β-glucuronidases have the ability to deconjugate glucuronides of some drugs, thus have been considered as an important drug target to alleviate the drug metabolites-induced gastrointestinal toxicity. In this study, thiazolidin-2-cyanamide de