52943-87-0

Upstream product

• 6402-09-1 1-(4'-nitrophenyl)-3-methyl-5-pyrazolone 
• 89-25-8 edaravone 
• 100-16-3 4-nitrophenylhydrazone 
• 41327-15-5 5-bromo-3-methyl-1-phenyl-1H-pyrazole 

Downstream Products

• 73225-12-4 3-methyl-1-(4-nitrophenyl)-5-phenyl-1H-pyrazole 
• 251655-52-4 1-(4'-Nitrophenyl)-5-(2-triisopropylsilylethynyl)-3-methylpyrazole 

Relevant academic research and scientific papers

Cross-coupling of 1-aryl-5-bromopyrazoles: Regioselective synthesis of 3,5-disubstituted 1-arylpyrazoles

The cross-coupling of 1-aryl-5-bromopyrazoles 4 with alkynes, vinyltins and arylboronic acids promoted by Pd(PPh3)4 afforded unsymmetrical 3,5- disubstituted 1-arylpyrazoles 5-8 in excellent yields, 1-Aryl-5- bromopyrazoles 4 were prepared from their corresponding 1-arylpyrazolones 3 with PBr3 in refluxing acetonitrile. (C) 2000 Elsevier Science Ltd.