52944-36-2Relevant academic research and scientific papers
Superacid-promoted synthesis of quinoline derivatives
Klumpp, Douglas A.,Stentzel, Michael R.,Vuong, Hein
supporting information, (2020/01/24)
A series of vinylogous imines have been prepared from anilines and cinnamaldehydes. These substrates react in superacidic media to provide quinolines and related compounds. A mechanism for the conversion is proposed which involves the cyclization of dicationic superelectrophilic intermediates. Aromatization of the quinoline ring is thought to occur by superacid-promoted elimination of benzene.
Insertion of Nitriles into Zirconocene 1-aza-1,3-diene Complexes: Chemoselective Synthesis of N-H and N-Substituted Pyrroles
Yu, Shasha,Xiong, Meijun,Xie, Xin,Liu, Yuanhong
supporting information, p. 11596 - 11599 (2016/02/19)
The direct insertion of nitriles into zirconocene-1-aza-1,3-diene complexes provides an efficient, chemoselective, and controllable synthesis of N-H and N-substituted pyrroles upon acidic aqueous work-up. The outcome of the reaction (that is, the formatio
Solvent-free synthesis, DNA-topoisomerase II activity and molecular docking study of new asymmetrically N,N′-substituted ureas
Andressa, Esteves-Souza,Rodrigues-Santos, Claudio E.,De Nigris Del Cistia, Catarina,Da Silva, Daniel Rosa,Sant'Anna, Carlos Mauricio R.,Echevarria, Aurea
, p. 12882 - 12894 (2013/02/22)
A new series of asymmetrically N,N′-substituted ureas 20-25 was prepared using solvent free conditions, which is an eco-friendly methodology, starting with Schiff bases derived from cinnamaldehyde and p-substituted anilines, which are subsequently submitt
A modular approach to α,β-unsaturated N-aryl ketonitrones
Hood, Tyler S.,Bryan Huehls,Yang, Jiong
supporting information; experimental part, p. 4679 - 4682 (2012/09/05)
A modular approach to α,β-unsaturated N-aryl ketonitrones has been developed. Specifically, condensation of anilines and enals followed by alkylation of the resulting α,β-unsaturated imines provided N-allyl anilines, which were subjected to oxidation with
Synthetic and mechanistic studies of indium-mediated allylation of imines in ionic liquids
Man, Chun Law,Tin, Wai Cheung,Wong, Kwok-Yin,Tak, Hang Chan
, p. 923 - 929 (2007/10/03)
(Chemical Equation Presented) Aldimines derived from aryl and non-enolizable aliphatic aldehydes were allylated with allyl bromide mediated by indium powder in [bpy][BF4] (bpy = N-butylpyridine) to give good yields of the corresponding homoallylic amines. Selective formation of monoallylated amines can be achieved by varying the amount of bromide ion additive in the form of [bpy][Br]. The transient organoindium intermediates, allylindium-(I) and allylindium(III) dibromide formed in the reaction, were studied by NMR spectroscopy to explain the selectivity.
Stereoisomeric Styryl-substituted Pyrrolidines, 3,7-Diazobicyclo[3.3.0]octanes and 2-Styrylpyrroles from Cinnamaldehyde Iminium-N-methanide 1,3-Dipoles
Butler, Richard N.,Farrell, Derval M.
, p. 82 - 83 (2007/10/03)
The reaction of cinnamaldehyde N-aryliminium methanide 1,3-dipoles with dimethyl maleate, dimethyl fumarate and some N-arylmaleimides gives equal mixtures of stereoisomeric substituted pyrrolidines and a route to 2-styrylpyrroles with dimethyl acetylene-d
Reactivity of Imines Towards 3-Trifloxypropeniminium and Propyniminium Triflates
Rahm, Rainer,Maas, Gerhard
, p. 1295 - 1304 (2007/10/02)
The imines 5 and 11 react with 3-trifloxypropeniminium triflates 1a-d to afford the heterocyclic iminium salts 8, 9, 13, 15, and 17, respectively, or the propeniminium salt 21.Propyniminium triflates 22, 24 react with imines by initial conjugated addition
