52948-10-4

Upstream product

• 20324-50-9 5-chloro-2-mercapto-benzoic acid 

Downstream Products

• 100871-62-3 5,5'-dichloro-2,2'-disulfanediyl-di-benzoic acid dihydrazide 
• 102880-99-9 5-chloro-2-(2-nitro-phenylsulfanyl)-benzoic acid methyl ester 
• 256947-58-7 methyl 5-chloro-2-sulfenamoylbenzoate 
• 4337-43-3 5-chloro-1,2-benzisothiazolin-3-one 

Relevant academic research and scientific papers

HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 -HYDROXYSTEROID DEHYDROGENASE

Disclosed is a compound which is useful as an 11β-hydroxysteroid dehydrogenase type 1 inhibitor. A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein X is O or S, a broken line and a wavy line represent the presence or the absence of a bond, (i) when a broken line represents the presence of a bond, a wavy line represents the absence of a bond, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, (ii) when a broken line represents the absence of a bond, a wavy line represents the presence of a bond, R1 and R4 are each independently hydrogen, halogen or the like, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, and R5 and R6 are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like.