5296-78-6 Usage
Uses
Used in the Production of Polyurethane:
ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE, 97 is used as a key ingredient in the production of polyurethane, a versatile material known for its wide range of applications. ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE, 97 contributes to the formation of polyurethane's unique properties, such as flexibility, durability, and resistance to various environmental factors.
Used in Insulation Industry:
In the insulation industry, ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE, 97 is used as a precursor for the creation of polyurethane foams, which offer excellent thermal insulation properties. These foams are utilized in various applications, including building insulation, refrigeration, and transportation, to enhance energy efficiency and reduce heat loss.
Used in Coatings Industry:
ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE, 97 is used as a component in the formulation of polyurethane coatings, which are valued for their durability, abrasion resistance, and adhesion properties. These coatings are applied in various industries, such as automotive, aerospace, and construction, to protect surfaces from wear and environmental damage.
Used in Adhesives Industry:
In the adhesives industry, ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE, 97 is used as a reactive monomer in the synthesis of polyurethane adhesives. These adhesives are known for their strong bonding capabilities, flexibility, and resistance to various environmental conditions, making them suitable for use in a wide range of applications, including woodworking, packaging, and automotive assembly.
Used in Foams Industry:
ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE, 97 is used as a raw material in the production of polyurethane foams for various applications, such as furniture cushioning, bedding, and footwear. These foams are appreciated for their comfort, support, and resilience, providing enhanced user experience in various consumer products.
It is crucial to handle ETHYL 2-ISOCYANATO-3-METHYLBUTYRATE, 97 with care due to its potential to cause irritation to the skin, eyes, and respiratory system. Proper safety measures, including the use of well-ventilated areas and appropriate personal protective equipment, should be implemented during its handling and processing.
Check Digit Verification of cas no
The CAS Registry Mumber 5296-78-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,9 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5296-78:
(6*5)+(5*2)+(4*9)+(3*6)+(2*7)+(1*8)=116
116 % 10 = 6
So 5296-78-6 is a valid CAS Registry Number.
5296-78-6Relevant academic research and scientific papers
Organosilicon synthesis of isocyanates: IV. Synthesis of isocyanates from aliphatic and alkylaromatic amino acid esters
Lebedev,Lebedeva,Sheludyakov,Shatunov,Ovcharuk
, p. 581 - 585 (2008/02/11)
Treatment of an alcoholic suspension of amino acids with trimethylchlorosilane yielded phenylglycine, valine, β-phenylalanine, and homovaline ester hydrochlorides. Their saccharin-catalyzed silylation with hexamethyldisilazane proceeds quantitatively and involves only one proton of the amino group. The best conversion of the amino acid esters to the corresponding isocyanates was achieved by phosgene treatment of their monosilyl urethanes, rather than of the silylated amino esters. Monosilyl urethanes are formed quantitatively by treatment of the amino acid ester hydrochlorides with the hexamethyldisilazane-CO2 system. The 1H NMR spectra show that monosilyl urethanes derived from α-and β-amino acid esters are characterized by intramolecular interaction of the silicon atom and the oxygen atom of the carboxy group. Nauka/Interperiodica 2007.
A convenient and efficient synthesis of novel 1-ethoxycarbonylmethyl-3-ethyl-1,2,3,4-tetrahydro-4-oxo- 1,3,2-benzodiazaphosphorin-2-carboxamide 2-oxides
Huang, Jun-Min,Chen, Hui,Chen, Ru-Yu
, p. 1357 - 1363 (2007/10/03)
Some novel 1-ethoxycarbonylmethyl-3-ethyl-1,2,3,4-tetra- hydro-4-oxo-1,3,2-benzodiazaphosphorin-2-carboxamide 2-oxides containing α-amino acid ester or α -aminophosphonate groups have been designed incorporating the proximate carbonyl and phosphoryl groups into the benzoannulated phosphidiamide heterocycle and synthesized by a convenient one-pot procedure in good yields, in which the hydrochlorides of α-amino acid esters or hydrobromides of α -aminophosphonates reacted smoothly with bis(trichloromethyl) carbonate with the help of four molar equivalents of triethylamine to give the corresponding isocyanates that then formed the products by the addition with the phosphorus reagent containing a P-H bond.
Design and synthesis of potent and selective inhibitors of integrin VLA-4
Wattanasin, Sompong,Weidmann, Beat,Roche, Didier,Myers, Stewart,Xing, Amy,Guo, Qin,Sabio, Michael,Von Matt, Peter,Hugo, Ronald,Maida, Susan,Lake, Philip,Weetall, Marla
, p. 2955 - 2958 (2007/10/03)
The synthesis and identification of a novel series of inhibitors of integrin VLA-4 are described. Their in vitro activity and selectivity against closely related integrins are also presented.
