52962-77-3Relevant academic research and scientific papers
A new reaction of 2-(phenylsulfonyl)-3-phenyloxaziridine (davis reagent): Oxidation of thiolates to sulfinates. Application to the synthesis of sulfones
Sandrinelli, Franck,Perrio, Stephane,Beslin, Pierre
, p. 1177 - 1180 (1999)
(Matrix Presented) The first efficient and general method for the generation of sulfinate anions by oxidation of the corresponding thiolates is described. The oxidizing agent employed is the classical 2-(phenylsulfonyl)-3-phenyloxaziridine, commonly known as the Davis reagent. Subsequent S-alkylation of the sulfinates under phase-transfer catalysis affords sulfones 6 in 71-91% isolated yields (10 examples).
Method for synthesizing 2,3-dihydropyrrole rings
-
Paragraph 0037; 0038, (2017/10/23)
The invention discloses a method for synthesizing 2,3-dihydropyrrole rings from p-toluenesulfonyl imine and disubstituted allene under the condition of a phosphine catalyst. The method is a convenient route for synthesizing 2,3-dihydropyrrole ring compounds without a metal reagent, and an obtained hydrogenated pyrrole product is a common basic structure in certain bioactive molecules and has potential pharmacochemical study value. The method for synthesizing the 2,3-dihydropyrrole rings adopts mild conditions and simple and available raw materials, and 2-position different substituted 2,3-dihydropyrrole compounds can be prepared conveniently.
