53005-72-4Relevant articles and documents
Half-Sandwich Ruthenium Complexes for One-Pot Synthesis of Quinolines and Tetrahydroquinolines: Diverse Catalytic Activity in the Coupled Cyclization and Hydrogenation Process
Yun, Xue-Jing,Zhu, Jing-Wei,Jin, Yan,Deng, Wei,Yao, Zi-Jian
, p. 7841 - 7851 (2020/06/04)
Four types of half-sandwich ruthenium complexes with an N,O-coordinate mode based on hydroxyindanone-imine ligands have been prepared in good yields. These stable ruthenium complexes exhibited high activity in the catalytic synthesis of quinolines from the reactions of amino alcohols with different types of ketones or secondary alcohols under very mild conditions. Moreover, the methodology for the direct one-pot synthesis of tetrahydroquinoline derivatives from amino alcohols and ketones has been also developed on the basis of the continuous catalytic activity of this ruthenium catalyst in the selective hydrogenation of the obtained quinoline derivatives with a low catalyst loading. The corresponding products, quinolines and tetrahydroquinoline derivatives, were afforded in good to excellent yields. The efficient and diverse catalytic activity of these ruthenium complexes suggested their potential large-scale application. All of the ruthenium complexes were characterized by various spectroscopies to confirm their structures.
Preparation of 1-indanones with conventional heating versus microwaves
Da Camara e Silva, Erick S.,Figueroa-Villar,De Aguiar, Alcino Palermo
, p. 3193 - 3198 (2007/10/03)
The acylation reactions of p-methylphenol with crotonic and 2-octenoic acids was carried out with the employment of conventional heating and irradiation by microwaves. The use of microwaves led to a significant reduction in the time of reaction from several hours to 2 min and 30-60% yield.
One-step Preparation of Some Synthetically Useful Indanones
Sarkar, Asoke K.,Sinha, Nitai C.,Dutta, Lakshmi N.
, p. 1061 - 1064 (2007/10/02)
Various indanones (2a-e) have been conveniently prepared in fairly good yields from phenyl esters of α-bromobutyrates (1a-d) in one-step through the application of Fries rearrangement followed by Friedel-Craft cyclisation.
CARBOXYALKYLATION OF ISOMERIC CRESOLS BY THE FRIEDEL-CRAFTS REACTION
Barashkin, V. A.,Kadyrov, Ch. Sh.
, p. 915 - 920 (2007/10/02)
The condensation of isomeric cresols with γ-butyrolactone and β-chlorobutyric acid in the presence of an excess of aluminum chloride leads to mixtures of isomeric β-cresylbutyric acids.The use of tetrachloroethylene as solvent in these reactions affects not only the yield but also the isomeric composition of the reaction products.
