5302-39-6

Upstream product

• 122-80-5 N-acetyl-p-phenylenediamine 
• 99-96-7 4-hydroxy-benzoic acid 
• 108-95-2 phenol 
• 108-24-7 acetic anhydride 
• 103-18-4 4-amino-4'-hydroxyazobenzene 

Downstream Products

• 103-18-4 4-amino-4'-hydroxyazobenzene 
• 1373771-76-6 C₂₀H₂₅N₃O₃ 
• 1380349-08-5 4-[4'-(4-acetamidophenylazo)phenoxy]phthalonitrile 
• 95747-67-4 4-Acetamino-4'-decyloxy-azobenzol 
• 95224-93-4 4-Amino-4'-decyloxy-azobenzol 
• 1421614-13-2 C₂₆H₃₇N₃O₃ 

Relevant academic research and scientific papers

Gadolinium containing photochromic micelles as potential magnetic resonance imaging traceable drug carriers

Novel photochromic amphipathic molecules, KMR-AZn (Gd-DTPA-AZCn), composed of hydrophilic Gd-DTPA and hydrophobic alkylated azobenzene were prepared. In aqueous environment, KMR-AZn indicated self-assembly. The resulting aggregates were demonstrated to be able to include a hydrophobic drug substitute (hydrophobic fluorescent dye) into the internal core, and to release the included compound upon photoirradiation within 10 min through the influence of azobenzene photoisomerization. This micellar MRI contrast agent exhibited three- to four-fold higher r1 relaxivity (r1 = 14.5-16.5 mm -1 s-1, 0.47 T at 40°C) than the widely applied small molecule contrast agent Gd-DTPA (Magnevistr1 = 4.1 mm-1 s-1, 0.47 T at 40°C). This dual functionality of encapsulated compound release and increased MR imaging contrast indicates that KMR-AZn is a potential candidate for application as a lipid-based MRI-traceable drug carrier.

Synthetic method of dye for polaroid

The method comprises the following steps: firstly, taking I acetamide-based aniline as a raw material, carrying out diazotization and coupling with phenol to prepare an intermediate with the structure of formula 4 - V. Step II is followed by etherification reaction of n-bromobutane under the action of an acid-binding agent to prepare the intermediate of formula IV. To the method, the acetamide-based phenylamine and phenol are subjected to diazotization coupling to have higher yield and purity, qualified products can be prepared without column chromatography, and the nitro reducing step with safety risk or environmental protection risk is avoided. The coupling compound 2 - piperidine -5 -aldehyde thiophene is coupled with the diazo component in the final coupling reaction, the coupling site takes place at the aldehyde group position, and the aldehyde group is removed in situ.

Photoswitchable Antagonists for a Precise Spatiotemporal Control of β2-Adrenoceptors

β2-Adrenoceptors (β2-AR) are prototypical G-protein-coupled receptors and important pharmacological targets with relevant roles in physiological processes and diseases. Herein, we introduce Photoazolol-1-3, a series of photoswitchable azobenzene β2-AR ant

Phthalocyanines with peripheral azo chromophores

Interaction of 4-halogenated phthalonitrile with arylazophenols provided 4-R-azophenoxyphthalonitriles that have been further transformed into tetra-4-(4′-arylazophenoxy)phthalocyanines and their metal complexes. Physicochemical properties of the prepared

Synthesis and properties of phthalonitriles with an azo chromophore and related phthalocyanines

The 4-R-phenylazophenoxyphthalonitriles were synthesized by the reaction of 4-bromophthalonitrile with 4-R-phenylazophenols and were used to obtain tetra-R-phenylazophenoxyphthalocyanines and their metal complexes. The effect of substituents on the spectr

Photo and electrically switchable behavior of azobenzene containing pendant bent-core liquid crystalline polymers

New class of photo and electrically switchable azobenzene containing pendant bent-core liquid crystalline monomers (AZBM 1, 2, and 3) and their polymers (AZBP 1, 2, and 3) are reported. The synthesized precursors, monomers, and polymers were characterized by FT-IR, 1H, and 13C NMR spectroscopy. Thermal stability of polymers was examined by thermogravimetric analysis and revealed stable up to 260 °C. The mesophase transition of monomers and polymers are observed through polarized optical microscopy (POM) and further confirmed by differential scanning calorimetry (DSC). The electrically switching property of monomers and their polymers were studied by electro-optical method. Among the three monomers AZBM 1, 2, and 3, AZBM 1 and 2 exhibit antiferroelectric (AF) switching and AZBM 3 exhibits ferroelectric (F) switching behavior. On the other hand, low molecular weight polymers (AZMP 1, 2, and 3) show weak AF and F switching behavior. The photo-switching properties of bent-core azo polymers are investigated using UV-vis spectroscopy, trans to cis isomerization occurs around 25 s for AZBP-1 and 30 s for AZBP-2 and 3 in chloroform, whereas reverse processes take place around 80 and 90 s.

Photo and electrically switchable B7 mesophase exhibiting asymmetric bent-core liquid crystals

The first bent-core liquid crystal materials with a photo-active azo linkage exhibiting the B7 mesophase are reported. The lower homologues of the bent-core compounds display the B1 phase and higher homologues show the B7 mesophase. The mesomorphic properties were characterized using polarized optical microscopy, differential scanning calorimetry and X-ray diffraction. The B7 phase of these materials establishes ferroelectric switching characteristics with anticlinic organization (SmCAPF) of the molecules in the layers. The bent-core molecules with an azo linkage are important for photoisomerization studies, which indicate trans to cis isomerization at 30 s, whereas the reverse processes take place over 40 s in chloroform.

Dynamic photo-control of kinesin on a photoisomerizable monolayer - Hydrolysis rate of ATP and motility of microtubules depending on the terminal group

The reversibly and repeatedly altered gliding motility of microtubules driven by kinesin on the photoresponsive monolayer surface is studied. It was confirmed that an azobenzene monolayer surface needs to have free amino terminal groups for the successful dynamic control of the motility of microtubule. The surface of the azobenzene monolayer with terminal amino groups can dynamically control the ATP hydrolysis activity of kinesin which resulted in the change in motility of the microtubules.