53078-69-6 Usage
Uses
Used in Pharmaceutical Industry:
2-Methoxy-4-Methylbenzonitrile is used as an intermediate in the synthesis of various pharmaceutical compounds for its unique chemical properties and reactivity. Its presence in the manufacturing process contributes to the development of new drugs and medications, enhancing their efficacy and therapeutic potential.
Used in Chemical Research:
In the field of chemical research, 2-Methoxy-4-Methylbenzonitrile serves as a valuable compound for studying the properties and reactions of phenylpropanoids and polyketides. Its unique structure allows researchers to explore new pathways and mechanisms in organic chemistry, potentially leading to the discovery of novel applications and compounds.
Used in Material Science:
2-Methoxy-4-Methylbenzonitrile may also find applications in material science, where its specific chemical and physical properties can be utilized to develop new materials with unique characteristics. Its potential use in this field could contribute to advancements in areas such as polymer science, coatings, and adhesives.
Safety Precautions:
Given the potential hazards associated with 2-Methoxy-4-Methylbenzonitrile, it is crucial to follow proper safety protocols during its handling, storage, and use. This includes wearing appropriate personal protective equipment, such as gloves, goggles, and masks, to minimize the risk of exposure. Additionally, it is essential to work in well-ventilated areas and follow waste disposal regulations to prevent environmental contamination.
Check Digit Verification of cas no
The CAS Registry Mumber 53078-69-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,0,7 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 53078-69:
(7*5)+(6*3)+(5*0)+(4*7)+(3*8)+(2*6)+(1*9)=126
126 % 10 = 6
So 53078-69-6 is a valid CAS Registry Number.
53078-69-6Relevant articles and documents
Lewis acid-promoted site-selective cyanation of phenols
Yang, Wen,Zhang, Wu,Zhao, Wanxiang
, p. 4604 - 4609 (2020/07/04)
An efficient Lewis acid-promoted site-selective electrophilic cyanation of 3-substituted and 3,4-disubstituted phenols has been developed. The cyanation reactions using MeSCN as the cyanating reagent proceeded efficiently to afford a wide range of 2-hydroxybenzonitriles with high efficiency and excellent regioselectivity. This protocol could provide a practical method for the synthesis and modification of biologically active molecules.
Nickel-Catalyzed Cyanation of Phenol Derivatives with Zn(CN)2 Involving C-O Bond Cleavage
Gan, Yi,Wang, Gaonan,Xie, Xin,Liu, Yuanhong
, p. 14036 - 14048 (2018/11/03)
An efficient nickel-catalyzed cyanation of aryl sulfonates, fluorosulfonates, and sulfamates with Zn(CN)2 was developed, which provides a facile access to the nitrile products in generally good to excellent yields. The reaction is accomplished by using NiII complex as the precatalyst and DMAP as the additive. The method also displays wide functional group compatibility; for example, keto, methoxy, N,N-dimethylamino, cyano, ester, and pyridyl groups are well-tolerated during the reaction process.
Electrochemical C-H cyanation of electron-rich (Hetero)arenes
Hayrapetyan, Davit,Rit, Raja K.,Kratz, Markus,Tschulik, Kristina,Goo?en, Lukas J.
supporting information, p. 11288 - 11291 (2018/10/20)
A straightforward method for the electrochemical C-H cyanation of arenes and heteroarenes that proceeds at room temperature in MeOH, with NaCN as the reagent in a simple, open, undivided electrochemical cell is reported. The platinum electrodes are passivated by ad-sorbed cyanide, which allows conversion of an exceptionally broad range of electron-rich substrates all the way down to dialkyl arenes. The cyanide electrolyte can be replenished with HCN, opening opportunities for salt-free industrial C-H cyanation.
